Allopurinol, aʻo i ka PAaIEN, laʻau heluna,ʻaoʻao 'ole a me nā contraindications

"Allopurinol", ke aʻo hoʻomōakaaka hookuu i loko o ka palapala o ka papa o ka 100 mg. Ua pili ia i ka lāʻau lapaʻauʻia protivopodagricakih 'o ia hoʻi inhibits ka hoʻololi kemikala o uricʻakika. E like me ka 'ole "allopurinol" ia mea he Analog o hypoxanthine, inhibitory nui'ūhū i' oe e komo i loko o ke kahua o uricʻakika. Ka lāʻau "allopurinol" hōʻike manaʻo hōʻoia mea e loli ai ka noho male 'ana o uricʻakika paʻakai, i hoopau wale o ko lākou hoʻonaʻauao' ia 'ana ma nā nā'aʻaʻa o ke kino, a ma nā puʻupaʻa.

"Allopurinol" ke aʻo ana i ka hoike

Ka lāʻau 'Ua kuhikuhi:
no ka pale, ana gout a me ka hyperuricemia (me ka huikauʻaʻa puʻuwai hoʻokō 'ole')ʻike, nephrolithiasis ,, urate nephropathy;
me ka kalipuna oxalate hakuʻala pohaku ma ka hui pu ana, me ka hyperuricosuria;
ma ke kiekie urate pae, i hanaʻia e like me ka hopena o enzymatic kāna hana;
no ka Kāohiʻana o ka huʻi nephropathy ma cytostatic, pāhawewe lapaau o kaʻeho, a leukemia;
ka wā 'inikua pololi.

"Allopurinol" aʻo i ka dosing

Ke Kauka nā pūʻulu ka mahele lāʻau o ka lāʻau ma luna o kekahi kanaka 'aelike ke kaumaha ma muli o ka
urate kaʻilikai ia akulla 'i loko o ke koko, a ma ka mimi, e like me ia ma ka lehulehu o uricʻakika. Nā mākua koho 100 mg "Allopurinol" mai i 900 mg no ka lā. Na kela la i keia mahele lāʻau Ua koi 'ia e mahele i loko o nā māhele 2-4. Nā papa E e ia ma hope oʻai.
Children ma lalo o ka makahiki o ke 15 kela la i keia mahele lāʻau pōpilikia me ka pololei e like me ka haʻilula: 10-20 mg no 1 kg kino ke kaupaonaʻana o ke keiki a lawelawe 100 mg "Allopurinol" i 400 mg.

ʻO kā mākou mahele lāʻau no nā mea maʻi me ka hihia hoʻi hakuʻala kuleana pili i ka 100 mg. Ke Kauka ke hoonui i ka mahele lāʻau ina ke kāʻei kua o ka iapaau ana koe ua hoʻololiʻia kiʻekiʻe kiʻekiʻe o ka urate loaʻa i loko o ke koko a me ka mimi.

"Allopurinol" alakai i kaʻaoʻao 'ole

Ma pohihihi keia hoopii, ua malama paewaewa ma ka mea'ōnaehana mānowai koko'ōnaehana, i hoikeia mai hypertension, bradycardia.
Hiki paewaewa ma ka digestive'ōnaehana i mea hōʻike:
nausea, ka luaʻi, diarrhea, transient mahuahua ma transaminases ike i loko o ka lāʻau lapaʻau;
hepatitis, ake dysfunction;
stomatitis (i loko o kanaka hoʻomanawanui iki mai);
steatorrhea.

Ma kaʻawale hihia "Allopurinol" lapaau ua kena ae la o kāna hana i loko o ka'emi'ōnaehana, i mea hōʻike:
nawaliwali, luhi, headaches, pōniuniu;
ataxia, sleepiness, kaumaha;
coma, paresis, paresthesia;
cramps, neuropathy;
pilikia makapō hoʻopilikia; cataracts;
loli i loko o ka 'ole o ka optic papilla;
dysgeusia.
Loa kākaʻikahi malama paewaewa ma ka hematopoietic'ōnaehana e i hoikeia aku ai e thrombocytopenia, agranulocytosis a me ka anaemia aplastic, leukopenia (kamepiula pae nā hoʻomanawanui iki mai ka poe i ua hoʻemiʻaʻa puʻuwai kuleana pili i).

Hiki paewaewa ma ka urinary'ōnaehana, i mea pohihihi keia interstitial nephritis; i kanaka e hoomanawanui i - edema, uremia, hematuria.

Haunaele ma ka endocrine'ōnaehana ana i loko o pohihihi keia hihia, infertility, impotence, gynecomastia, mimikō.
Metabolic kāna hana hoike ma kekahi mau hihia hyperlipidemia.
Allergic ole dermatological adverse reactions.

"Allopurinol" aʻo i nā contraindications

He mea hiki ole ia i koi 'ia i kekahi lāʻau:
i loko o kāna hana o ke akepaʻa, hakuʻala;
Hāpai keiki, a lactation;
ma ka hihia o ka hypersensitivity i ka "Allopurinol".

Ma lapaʻau hana, na keiki ma lalo 12 makahiki o ka makahiki, "Allopurinol" hoakaka wale no o ka iapaau ana o malignant hikoko, ma ka leukemia, ana'ūhū kāna hana, e like me Lesch-Nihena maʻi pale.