"Atorvastatin": nā mana'o ho'ohālikelike, nā analogues, ka mele a me nā kuhikuhi no ka ho'ohana'ana

'O ka lā'au lapa'au ma'amau i hana'ia e hō'emi i ke ki'eki'e o ka cholesterol a me ka LDL'o "Atorvastatin." 'O nā mana'o o nā po'e ma'i e pili ana i ia mea he mea ma'amau,'oiai ke hō'oia'ia ka maika'i o ka lā'au lapa'au e nā noi ninaninau. I kēia kū'ana, ho'okahi wale nō mea ho'okūkū o ka lā'au lapa'au -'o "Rosuvastatin" (a me kona'ano). No laila, maopopo ke'ano o nā loiloi ho'omanawanui e hiki'ole ke hā'awi i nā'ike kūpono e pili ana i ka lā'au'ona "Atorvastatin". No laila, no ka loiloi i kona mau hopena, kahi'ike piha'ana i ka hana o ka hana a me nā kuhikuhi o nā kuhikuhi i ho'ohui'ia no ka ho'ohana.

'O ke'ano ma'amau o ka mea lā'au lā'au

'O ko Atorvastatin ka waihona o ka'oihana kālaihana o nā hanauna o ka hanauna'ekolu. Ma ka pāpā 'ana i nā enzymes i kuleana no ke ka'ina o ka cholesterol, ka nui o ka ha'okikoki atherogenic o lipoproteins e emi iho ana. 'O nā'āpana ha'aha'a li'ili'i (LDL) hiki ke ho'onui i ka lawe'ana o ka cholesterol a hana i nā mea kūpono'ole i ka melikelamu, ka mea e ho'oulu ai i kahi pāpale.

E like me nā'ano'oko'a, ho'onanei nui ke atorvastatin i ka nui o LDL, a no laila ho'onui nui i ka ulu'ana o ka plaque. Ma keia ka welelau o i kona involution ua i mālama, a me ke anawaena o ka coronary artery ( 'ole kekahi' ē atherosclerotic), e waiho ana no ka ia. 'O ka hopena o ka hopena - ho'opi'i i ka ulu'ana o ka IHD, cerebrovascular, a me ka lawa'ole o ka ho'opa'a'ana o nā mea ha'aha'a.

Atorvastatin: kuhikuhi no ka ho'ohana

Ma mua o kāu ho'omaka'ana e pono ia e ho'oholo i nā hō'ailona no ka ho'ohana'ana i ka lā'au lapa'au. Holo lākou mai ka mana nui o kāna hana a pili i ka hopena hypocholesterolemic. Ka pae o nā hō'ailona:

• Ka loa'a o ka homeralesterolemia heterozygous;
• 'O ke kālepa o ka papa IIa o Polygenic (primary) e like me Fredrickson;
• 'Ahui'ia (IIb) dyslipidemia;
• 'O ka hypercholesterolemia ma'amau'ohana Homozygous;
• 'O ka Hypertriglyceridemia (me ke'ano o ka lā'au me ka'ai'ana);
• Nā kūlana e pili ana i nā'eke atherosclerotic o ka pāpa'i o ka na'au, ka lolo, nā pu'upa'a, nā lālā;
• hypertension me ke kiʻekiʻe mea'ōnaehana mānowai koko kamepiula;
• Ka palekana'ana i kahi hanana hō'ailona hihia e pili ana i ke kumu o kahi lepe o ke atherosclerotic o ke anakē kalahau;
• 'O ka pale'ana i ka hō'ailona kūpiliki'i a me ka hō'eha o ke kino.

Hō'ike kēia mau hō'ailona i nā hihia ke ho'ohana'ia ka ho'ohana'ana i ka lā'au "Atorvastatin". Ma nā hō'ike a nā kauka i kāna noi e hō'oia'i'o i kēia pono. 'O ka hō'oia'i'o'o ia'o nā statins, e like me'Anorvastatin me kona mau'ano he nui, ua'oi aku ka palekana ma mua o ka cardioform acid acetylsalicylic, akā e kōkua nō ho'i lākou e hō'emi i ka likelike o ka ho'omohala'ana i ka'eha hope'ole me ka'ōlelo hou.

Ho'ohālike like'ole

'O nā papa a pau "Atorvastatin", nā hō'ike e pili ana i kahi e hiki ai iā'oe ke heluhelu i lalo, nā huahana pharmacological i hana'ia. 'O ka hapanui pinepine, ua ho'ololi'ia nā inoa o nā lā'au lapa'au, a hiki iā lākou ke ho'okae'ia. 'O nā inoa inoa o nā analogues,'o ia ho'i, nā ho'omākaukau'ana i loko o ka toorvastatin ma ke'ano he mea hana ikaika, penei: "Anvistat" a me "Atokord", "Atomas" a me "Ator", "Atorvox" a me "Atoris", "Vazotor" a me "Lipofford" Liprimar a me Liptonorm, Novostat a me Torvazin, Torvakard a me Tulip.

Eia kekahi, ke hana nei kekahi po'e mea hana i kā lākou iho pono'ī "Atorvastatin" (hiki ke heluhelu'ia ma lalo) ma lalo o ka inoa'oihana like. Aktavis, Vertex, Izvarino Pharma, ALSI Pharma, Canon Pharma, Kamupene'ona o Obolensen, Protek-SVM, Severniah Zvezda, TABUK Pharmaceuticals, TEVA Pharmaceutical Industries a me kekahi mau mea hana i ka lā'au lā'au, ka inoa 'Oi'ia ka INN ("Atorvastatin") a me ke ki'i mua. Eia kekahi hi'ohi'ona'o "Atorvastatin Teva", a ua hō'oia'ia e kona'ano pono.

'O ka hui

Pili ana i ka lāʻau 'atorvastatin' aʻo no ka hoʻohana, hōʻike manaʻo a me ka lapaʻau lula mai i apo ia 'ike e pili ana i na oko ma waena o ka laʻau heluna pepa. I ka'oihana, aia nā'ano like'ole, a ke ho'oponopono nei lākou i nā hana o ka hopena maika'i. 'O ka mea nui'o ia ka wikiwiki o ka hopena o ka hopena o ka hō'ailona. 'O ia ke kumu o ka ho'ohana'ana o ka lā'au lapa'au "Liprimar"'o ia ka kuhikuhi.

'O ke'ano o nā mea hana ke'ano o ka calioum atorvastatin a me ka uhi'ana i ka papa. Ka hope, i ka huli, oia o ka pōhaku paʻapuna, microcrystalline kelulose, lactose monohydrate, polysorbate 80, paʻakai croscarmellose, makanekiuma stearate, hydroxypropylcellulose, talc, titanium'okikene lua, polyethylene glycol, hydroxypropylcellulose, simetikonovoy emulsion, benzoic a me sorbicʻakika.

Ho'okomo'ia me nā'ōlelo kūikawā'o "Atorvastatin" i nā'ōlelo a'o no ka ho'ohana'ana (hō'ike hou i kēia)'a'ole i loa'a ka'ikepili i ka nui o kēlā me kēia hui. He mea hūnā ki'i kēia no ka PFIZER HCP CORPORATION o'Amelika. 'O kēia'ano kēia o ka liparid lip dosar e hiki ai ke ho'okō i ka ho'omau pinepine o ke atorvastatin i loko o ke koko.

Nā'ano hui pū'ia o "Atorvastatin"

Ma ke kau lā'au "Atorvastatin" ke kumukū'ai (nā mana'o o nā ma'i e hō'oia ana i kēia) e noho mau ana i nā ma'i lehulehu. He lā'au lapa'au maika'i loa kēia e hiki ke ho'ohui'ia me nā papa lā'au'ē a'e. 'O ka mea pinepine, "Atorvastatin" a me nā mea'ē a'e i hana'ia i kahi ka'awale,'o ia ho'i, ma ka papa ho'okahi wale nō mea waiwai. Eia na'e, ua hui pū'ia kekahi.

Eia nā'ano'apa'au: "Kaduet", "Duplexer", "Statinam." Ma'ane'i, hui pū'ia ka "Atorvastatin" me ka amlodipine, ka mea loka o nā kahawai calcium, kahi i ho'ohana pinepine'ia no ka mālama'ana i nā ma'i o ka na'au. 'O ke'ano o ia lā'au lapa'au ua koho'ia e ke kauka.

Nā papahana ma'amau o "Atorvastatin"

'O ke kau lā'au "Atorvastatin", nā hō'ailona no ka ho'ohana'ana, nā mana'o a me nā'ōlelo ho'ohui no ka ho'ohana'ana i ka hopena a mākou e nānā ai i loko o kā mākou loiloi, aia ma loko o'ekolu mau kuhina: 10, 40 a 20 mg. 'O ka ho'olauna hui'ia "Kaduet" he 10 mg o ka atorvastatin a me 5 amlodipine. Aia nā "Statins" ma nā'ano'elua: 10/5 a 10 / 10mg. 'O ka ho'omākaukau'o Duplexer he 4 mau atonvastatin a me amlodipine: 10/5, 10/10, 20/5, 20/10 mg. Kēia ho'ēmi i kā ka helu o nā papa i nā mea maʻi, ka poe i ka hana a me ka statins a me kalipuna Kanal blockers no ka iapaau ana o ka maʻi. Ho'ohālike kēia i ka uku o ka lā'au ola.

Ke koho'ana o nā analogues o "Atorvastatin"

'O ka mea mua e loa'a ai i ke atorvastatin, i kū'ai'ia,'o ia ka "Lipimar". 'O kēia ka lā'au lapa'au mua kahi i hana'ia ai nā ho'okolohua. Ma hope mai, ua hana'ia nā mea'ē a'e ma lalo o nā inoa'ē a'e. No kā lākou ho'opa'a inoa'ana,'o ka hō'oia'i'o'ana o ka bioequivalence no Liprimaru. I kēia manawa, hiki i kēia ke ho'onani i kekahi mau mea hana. No laila, i ka loa'a'ana mai o ke kauka i ka palapala no nā analogues i loa'a ma ka lā'au'o "Atorvastatin", e pono ke a'o pono'ia nā'ano e pili ana iā lākou.

Mana'o pinepine ke kauka i ka lā'au lapa'au, a ua hō'oia i kona bioequivalence i "Liprimaru" a he kuleana maoli nō i ho'ākāka'ia ma nā kuhikuhi i kau'ia. 'O ke kumukū'ai o Liprimar he mea kū'ai aku,'a'ole ia e ho'opili i kāna kū'ai'ana no ka lā'au lapa'au. Eia na'e,'a'ole e hā'awi'ia i nā po'e ma'i me nā pono o ka wā i loa'a no ka hemahema no ka ma'i ma'amau. I ka manawa like, ke mālama'ia nei nā lā'au lapa'au e hiki ke ho'opuka'ia e ka Center for Expertise and Testing in Medicine. Ua'ike'ia kā lākou pono.

Nā'ōlelo a nā po'e ma'i no'Ateravastatin

No ka lā'au'ona "Atorvastatin" o ka mea ho'omanawanui hiki'ole ke ma'a, no ka mea, me ka loiloi'ole o ka lipidogram'a'ole hiki ke koho i ka hopena o ka lā'au lapa'au. No laila, i mea e maopopo ai ka pono, pono pono e ho'oka'ina i nā loli o nā hakina lipid. Ma ka manawa ho'okahi,'o kekahi "Atorvastatin", i ho'olaha nui'ia, aia nā'ike e pili ana i ka hopena kūpono. Pa'a pinepine nā hopena ma'i. 'O ka'awa'awa o ka lā'au lapa'au he mea ha'aha'a a'ike pinepine'ole'ia. Eia nō na'e, ma nā hihia, me ke'ano o ka ma'i cytolysis a me ka pi'i'ana'ekolu o ka transaminases, pono ka wehe'ana i ka lā'au hō'ailona.

Hō'ike ka po'e ma'i i ka hopena o nā mea'ino. No kēia kumu, he nui nā po'e ma'i e'ōlelo i ka lā'au lapa'au no nā mea'ike a pili paha,'oiai'o ka ho'onohonoho'ana e pono e kūkākūkā me ka ho'oponopono, ka nānā'ana i nā pilikia a me ka ho'oholo'ana i nā hapahā lipid. Eia kekahi, he nui ka po'e e hā'awi i nā lā'au lapa'au'ole, no ka mea, he mea ho'emi ia i ke kaumaha o ke kino.

Akā, pono mākou e nānā pono aku i nā mana'o i loa'a e pili ana i ke lā'au'alo "Atorvastatin". No ka poho kaumaha,'a'ole pono, akā hiki ke kau'ia me nā kaumaha a me ka'ai. Alu hoʻohana "atorvastatin" a me nā lipid-hakumakuma konohiki, e like me ka ua pinepine paipai i kanaka me ka 'inikua aʻo, hiki aku ai i rhabdomyolysis a me ka ake kaʻawahia.

Nā'ike o nā kauka e pili ana i ka lā'au lā'au

No ka lā'au lapa'au "Atorvastatin" ke mana'o o ke kauka he'oi aku ka nui ma mua o ka mana'o o ka mea ma'i. Ho'ohana like kēia i nā lā'au lapa'au'ē a'e. Ma ke'ano laulā,'o nā hopena o nā hō'ike a nā loiloi ke'ano o ka palekana o ka lā'au lapa'au a me kona pono. Ho'oemi'ia ka cholesterol a me ka LDL, i ka ho'onui'ana i ka HDL. He mea nui kēia, no ka mea, hiki iā'oe ke ho'omalu i ka ulu'ana o ka plaque atherosclerotic a ho'olā'ihi i ka ulu'ana o ka hō'ino'ana o ka myocardial.

'O ka ho'oikaika o ka hopena hypocholesterolemic i loko o ka lā'au'ona "Atorvastatin" (kahi hō'ike o nā mea a pau i nā kauka ke hō'oia i kēia) he mea hō'ike loa. Ho'omaopopo ka Normalization o ka hō'ike lipid o ke koko koko ma hope o 1.5-2 mahina. Ma "Rosuvastatin" ua ho'okō'ia kēia ma 30 mau lā. Eia na'e, i kēia wā, "Atorvastatin" i'oi aku ka nui o nā lā'au noi'i, e hō'oia'i'o ana i kona pono a me ka palekana. Ma ke'ano laulā,'elua mau lā'au maika'i maika'i, hiki ke ho'ohana'ia kēlā me kēia mea e hana i ka hypercholesterolemia a pale i ka ma'i ma'i.

'O ke kumu kū'ai lā'au

I ka lā'au'ona "Atorvastatin" (ke'ano o nā'ano he nui o kēia vydeliyut) e pili ana i ka mea hana. 'O ke kumukū'ai nui loa'o ia'o "Lipimar" -'o ke kaukō maoli. 'O ka uku o ka mālama'ana i nā mahina he 900-1100 rubles me kahi 40 mg. I ke ola o 20 mg, ke kumu kū'ai no ka lapa'au he 800-900 rubles. Generics "Lipua" nui loa aku.

'O ke kumukū'ai o ho'okahi malama o ka lā'au lapa'au me ka lā'au "Atoris 40 mg" he 500 rubles, a he 20 mg - 200 rubles. Ma ka manawa like, "Atoris" kahi lā'au "liprimaru"'o Bioequivalent e ho'opiha loa ia. Eia kekahi mau māmala li'ili'i: Torvacard, Lipitor, Torvas, ke kumu kū'ai o ka mālama'ana i kēlā me kēia mahina i 40 mg mau hua, e'oi aku ka maika'i ma mua o 300 rubles. A'o ke kumukū'ai o ka ho'omeheu me 20 mg mau lā he 100-150 mau'āpana.