Desensitizing konohiki: i ka papa inoa a me ka hōʻikeʻano

Desensitizing konohiki (antiallergics, antihistamines) - ai 'ana i ua hoʻohana ma o ka iapaau ana o allergic ana. Keʻano papa hana o ka hana o ia mea ua hoike mai ia ma ka palapala o ka paleʻana i ka H1-histamine receptors. Nolaila, he suppression o histamine 'ole - ka papa kuhikuhiE uwao waiwai e hoʻolako loa o ka helehelena o allergic symptoms.

Histamine hōʻike 'mai ka holoholona nā'aʻaʻa i ka 1907, ma ka 1936, a me ia, me ka ai' mua i loaa i inhibited i ka hopena o keia waiwai. He haʻawina paipai ana ia mea ma kona hopena ma gistaminoretseptory naehana'ōnaehana,ʻili a me ka maka ke kumu i ka typical symptoms o allergies a me antihistamines ke uhi i kēia naoh.

Mea Maluna o ka desensitizing konohiki ma keʻano papa hana o ka waiwai ma luna o nāʻano o nā allergies:

• lapaʻauʻia no ka koke type allergic reactions.

• lapaʻauʻia no ka hoolohi-type hypersensitivity.

Lapaʻauʻia no ka koke type allergic reactions

1. Agena i inhibit i ke kala o allergic uao mai malimali Muscle keena a me basophilic, me ka malama inhibition o ka cytotoxic cascade o allergic naoh :

• β1-Adrenomimeticalkie kālā;

• glucocorticoid;

• myotropic antispasmodic loa.

2. Stabilizers aeea membranes.

3. blockers H1-histamine mea loaʻa keena.

4. Desensitizing.

5.ʻO nā mea kūpale o ka hoʻokō nenoaiu.

Luna e hana ana ma ka hoolohi-type hypersensitivity

1. NSAIDs.

2. Glucocorticoid.

3. Cytotoxic.

pathogenesis o allergy

Ke pathogenetic hooulu ana o ka allergy Radio ua synthesized he nui kūlana o ka histamine mai histidine, a ua waihoia ma ka basophils (kia aeee), ka connective'aʻaʻa (me ke koko) platelets, eosinophils, lymphocytes, a me liluwelo fluids. Histamine ma na keena poe deaktivnoy pae hui me nā polokina, a polysaccharides. Ua Ua hookuu ma muli o ia i kekahi me mechanical kina aeea,'ōnaehana paleʻea reactions, ma lalo o ka aoao o Nine Inch huahana a me pharmaceuticals. Inactivation ia lŘlŘ Via kona histaminase o mucosal'aʻaʻa. Ho'ā 'ia paha H1 receptors mea excitesʻili lahilahi phospholipids. Aie i ka Nine Inch reactions, nā kūlana e hoʻonui ai i ka anal i loko o ka halepaahao Ca, a me ka hope hana ma luna o nāʻalā Muscle contraction.

Hana gistaminoretseptory h2 histamine hiki aku ai i kaʻeleu adenylate cyclase a me ka piʻina ma ke kelepona hele e hoʻomoana ai? Iecaianoaaiiie, ka mea e hookomo ana i ka hua ma ka secretion o ka gastric mucosa. Penei, e hoʻohana 'ia kekahi desensitizing konohiki e emi i ka secretion o HCl.

Histamine produces capillary mailaila aku hoʻolako amplification permeability o vascular pā, edematous pane, hoemi wai koko ka leo, i hiki aku ai i ka hanaʻia naʻe o ke koko, ka ho'ēmiʻana i loko o ka arteries, bronchial ala apuupuu Muscle contraction, ahu iho no e ae hookaawale H1 gistaminoretseptorov; hoʻoikaika 'ana i ka adrenaline kalaʻana aku, kokololio Kal.

Hana ma luna o ka H1 receptors o endothelial capillary pā, histamine ke hookuu aku oia prostacyclin, ia hoʻokāʻoi aʻe ana iʻae mai o na moku liilii, (ka oi aku venules) Aoao koko ma loko, ua haule ma ka ai hoʻolahaʻia ke koko buke, keia e hōʻoiaʻiʻo ana i ke kala o ka wai koko, nā polokina a me ke koko keena ma ka, ua kīkoʻo akula paia mezhendotelialnogo ka lewa.

Mai na kanalima o ka 20th kenekulia. a hiki i neia wa desensitizing hoomakaukau ana alaila kuu aku la me ka hoopuka moakaka loli. ʻepekema, ua kauoha aku e hana hou ai 'me ka poʻeʻuʻukuʻaoʻao waiwai, a me ka papa inoa o ka nui ka hoʻokōʻana. Ma ka keia ke kahua, he mau ekolu papa kuhikuhiE pūʻulu o antiallergic ai ': mua, ka lua a me ke kolu o hanauna.

Desensitizing konohiki o ka hanauna mua

Desensitizing konohiki 1st hanauna hiki wawe ka hele ana ma ke koko-lolo ke'ākeʻakeʻa mai (BBB) a ua pili i ka gistaminoretseptorami cortex. Kēia desensitizing he hoʻonui i ka kiaha dala waiwai, e like me ia ma ka palapala o ka uuku drowsiness, a ma ke ano o ke kani hiamoe. Medsredstva 1st hanauna aiiieieoaeuii lakou aloha ia psychomotor lolo naoh. No keia kumu, kā lākou hoʻohana ua kaupalena i loko o kekahi pūʻulu o nā mea maʻi.

An hou hopena maikaʻi wahi mea i hoʻok & hana me ka acetylcholine, no ka mea, i kēia mau ai 'ke pāʻani aku me muscarinic nā aʻalolo a hāʻule pahū like acetylcholine. No laila, koe wale no ka mea malimali hana o kēia mau ai 'i maloo waha, constipation, a me ka tachycardia.

Desensitizing 1st hanauna cautiously hoakaka no ka glaucoma, ulcers, naau ahulau, a ma ka hui pu ana, me ka antidiabetic a me ka psychotropic ai '. Lakou e ole lawe oi aku mamua o na la he umi aie i ka mea hiki, e alakai i ka 'ino.

Desensitizing konohiki 2nd hanauna

Mau ai 'i He kiʻekiʻe loaʻo Solomona me ka histamine receptors, a he e wae waiwai, pela e hana ma luna o ka muscarinic receptors. Eia hou kekahi, ka mea i wehewehe aku e haahaa anal ma ka BBB, a i ole addictive, mai paka sedation (kekahi manawa ma kekahi mau hoʻomanawanui iki mai i ka hiki e hoopuni drowsiness).

I ka pau ana o ka? Eaia o ka pākōlea hopena o ka ai 'ke kali i 7 lā.

Kekahi noho Anati-hoʻoʻino loa, cardiotonic hopena. Ka hope keakea ponoʻana mai o ka mea'ōnaehana mānowai koko'ōnaehana i ka manawa o ko lākou komo.

Desensitizing konohiki kolu o ka (hou) hanauna

he hou ka hanauna o ka antisense ai 'i wehewehe aku e kekahi selectivity kiʻekiʻe i ka gistaminoretseptoram. Ka mea, e mai i sedation, a i ole pili i nā ipu naau a me ke koko.

Hoʻohana ana i kēia mau ai 'hoao ia iho iloko o hooloihi ae i antiallergic Inc - lapaʻau o allergic rhinitis, rhinoconjunctivitis, urticaria, dermatitis.

Desensitizing ai 'no ka keiki

Allergy lapaʻauʻia no nā keiki e pili ana i ka hui H1-blockers, a antisense ai '- he lāʻau manao ia no ka iapaau ana o kela allergic reactions i loko o ke kino o ka keiki ka. Ma keia pae ana o kūlana hana nei:

• I hanauna.

• II hanauna.

• III hanauna.

Hoomakaukau no na keiki - I hanauna

He aha ka mea, desensitizing ai '? Papa inoa ia i hōʻike mai iā ia ma lalo:

• "Fenistil" - rekomenovan na keiki mua ma mua o kekahi mahina i loko o ka palapala o nā paka ua.

• "Diphenhydramine" - ma luna o ehiku mahina.

• "Suprastin" - oi ma mua o hoʻokahi makahiki. Ma mua o ka mea i hoonohoia ma ka wale injectable palapala, a ma lalo o 'inikua hooponopono ana o ke kauka wale.

• "Fenkarol" - oi ma mua o na makahiki ekolu.

• "Diazolin" - ma ka makahiki o ka elua.

• "Clemastine" - ma ka makahiki o eono, ma hope o 12 mahina. i loko o ka palapala o ka malakeke a me ka pahu kui.

• "Tavegil" - ma ka makahiki o eono, ma hope o 12 mahina. i loko o ka palapala o ka malakeke a me ka pahu kui.

Hoomakaukau no na kamalii - II ia hanauna aku

Ka loa, he pono ole desensitizing ai 'o kēiaʻano.

• "Zyrtec" - oi ma mua o eono mahina i loko o ka palapala o ke kulu, a ma luna o eono makahiki ma ka papa palapala.

• "Claritin" - oi ma mua o nā makahiki.

• "Aerius" - oi ma mua o kekahi makahiki i loko o ka palapala o ka malakeke, a ma luna heʻumikumamālua makahiki i loko o ka papa palapala.

Hoomakaukau no na kamalii - III hanauna

Desensitizing konohiki o kēiaʻano nā:

• "Astemizole" - oi ma mua o nā makahiki.

• "Terfenadine" - makahiki hou ma mua o ekolu ma kau palapala a me ka makahiki hou ma mua o eono i loko o ka papa palapala.

E manaolana aku kakou i keia 'atikala mea i loko o ke koho ana o Anati-allergic ai' no ke kino (a ole wale) i ke keiki i ka, e kōkua ho okele a e ka wae akau. Naʻe, ka mea e e kaulana ia ma mua i ka hoʻohana 'ana i ia mau lapaʻauʻia pono eʻoiaʻiʻo, e heluhelu i nā kauoha, a e hiki ke hana ia me ka nīnau: "desensitization ai' - He aha ka mea?". Oe E hoi imi 'inikua'ōlelo aʻo.