Ka lāʻau "Metozok": aʻo no ka hoʻohana, analogs a me nā hōʻike manaʻo

naau maʻi a me ka ipu koko i ko ka hailona ana o kanaka. E hoʻopau i kēia mau maʻi puʻuwai, i hoakaka ia "Metozok". Na Ke Kumu no ka hoʻohana ua ikaika pono ma mua ka hoʻohana 'ana i kēia mau huaale nīnau aku i ke kauka, a mai lawe i ka lāʻau ma luna o lākou iho, no ka mea, he contraindications nui. Ka lapaʻauʻia ke kōkua pū mai i loko o nā maʻi angina, loa naau e hemahema, tachycardia, migraine a me ka like maʻi puʻuwai.

'ole

Kuhikuhi o ka mea o "Metozok". Na Ke Kumu no ka hoʻohana wehewehe i au mamuli o ka haku mele 'ana o ka papa.

A medicament me ka laʻau heluna o 25 mg ec 23,83 mg oʻeleu 'Oponopono metoprolol tartrate, 50 mg mea e pili ana 47,66 mg oʻeleu' Oponopono a me 100 mg - 95,32 mg.

Adjuvants haku o ka lapaʻauʻia e: hypromellose, ludipress LTSE, povidone, colloidal silikone'okikene lua, makanekiuma stearate.

Papa ka penaʻana ninoieo o ka hoomakaukau-i waiwai "Opadry II», a ua penaʻia i loko oʻalani. Ua nā eiiiiiaiou e like me Tewetewe ka waiʻona, talc, macrogol, titanium'okikene lua, yellow hao'okesaside 'ia nā pōpō, ulaula a me kaʻeleʻele, a me ka indigo.

Papa ho i ka lōʻihi-hana ka lapaʻauʻia, ua uhiia lakou me ka kukui-omaomao wahī. He hoʻopoepoe, convex ma nāʻaoʻaoʻelua.

Dragee i loko o ka nui o ka 30 na apana i piha i ka ea o na hue, a he 10 apana ma ka Aluminum blisters. Ka pepa pahu be ekolu blisters.

Hookah "Metozoka" He He Lūkini poe JSC "Akrikhin".

Pharmacological hana a me ka farmadinamika

I kapa i ka cardioselective beta1-blocker Akala a "Metozok". Na Ke Kumu no ka hoʻohana loa wehewehe i ka pharmacological hana o ka lāʻau. Ka lāʻau 'ʻAʻoheʻili lahilahi stabilizing ka waiwai a me ka sympathomimetic aayoaeuiinoe. Wehewehe aku antihypertensive, antianginal a me ka antiarrhythmic hana.

Small dala β1-adrenergic receptors 'aʻole hoʻi i ka naʻau, emi ho'ā hope o ka catecholamine hui e hoʻomoana ai, mai ATP, minimizes pono i loko o ke kalipuna Ion,' ano apau loa o ka io chronotropic, BATM, dromo- a me ka inotropic 'ole. I ka hoʻomaka o ka lāʻau i maoli he ka ia'ku ipu nohona ma. He mea pono i ka stimulation o ka α-adrenoceptor wahi a β2-adrenoceptors. Ma hope o kekahi mau lā (1-3), ka hoʻomanawanui hoike i ka palapala, akā, me ka lōʻihi-makahiki Inc ho'ēmi i kāʻike ākea vascular e kū'ē'ē mai.

Antihypertensive hopena ia lŘlŘ ma ka hoemi i ka helu o ka minuke i koko, a me ka renin i huiʻia ma inhibition hope o ka papa renin-angiotensin-aldosterone a Central ko mākou hopohopo'ōnaehana, e like me ka hou ana o ka susceptibility o na baroreceptors o ka aortic e pio mai, a me ka hope hoemiiaʻike ākea kōkua aloha o na kii. Emi ke kiekie ke koko, i loko o ka ilina kulana. Puʻe ka ho'ēmiʻana ia lŘlŘ ma physical haʻawina a me ka manaʻoʻike stress. Ke antihypertensive ia mau no ka oi ma mua o ka lā.

Antianginal waiwai hoike mai ai ia i ka emi ma myocardial o oxygen e pono ai, a ultimately ho'ēmi i kā ka naau i kela a me Muscle susceptibility i ka aoao o ke aloha o innervation. Ua ho'ēmi i kā ka helu o ka ho'āhewa wale 'o angina pectoris a me ka hōʻemiʻana i ko lakou lōʻihi like' ole. Hoonuiia physiological ha awina o ke kanaka. Aie i ka mea ulu o ka hoopau ana i ke diastolic puʻe i loko o ka ventricle hema, a me ka elasticity o na nāʻiʻo o nā ventricles maoli i ka pono no ka o oxygen i loko o kanaka e loaa ana mai ka naʻau ole.

Antiarrhythmic hopena ua loaʻa suppression arrhythmogenic hoike ana i hoʻohikiʻia me tachycardia, hypertension a me ka mea e like. D. mākaukau kaua paha ma unexpected ka ho'ēmiʻana o ectopic excitation a me ka sinus pāpana, a me ka inhibition o door-ka hoʻokō 'ia.

Ma ke alo o ka tachycardia, supraventricular a me ka sinus hoʻokino kaʻimiʻana atrial fibrillation, thyrotoxicosis a me nā maʻi iaea ooieoeiiaeuiiai cardiac lima kūlana kiʻekiʻe emi ka naau ana, a ma kekahi manawa hele aku ai a hiki i ka hoihoi hou ia ana o ka sinus pāpana.

I ka lāʻau o ka prophylactic maikaʻi ma luna o migraine.

E like me ia i loko o ka hapalua like-pākōlea nā māhele,ʻaʻohe nō ia ma luna o nā nā loko me ka β2- adrenoceptors, aʻaʻohe kanawai ma metabolic keʻano o ka hanaʻana i loko o ka o carbon kino. Kona hookoia mea i 'ano like me ke kanawai o ka "Propranolol".

I ka loaa ana i ka lāʻau no kekahi mau makahiki, hiki me ka nui loa emi ka nui o ka naʻokoko i loko o ke koko. I ka loaa ana i kela la nā māhele o ka 100 mg lāʻau e loli ai i ka poʻe i nā mea a pau β-adrenoceptor subtypes.

"Metozok" (manual ke hele mai me ka huaale) hōʻuluʻulu manaʻo ma ka 95%. Moderately wailana ma ka momona. Ua komo i loko o mua-alahele pūnao a me ka bioavailability ka 50% ma ka loiloi mua pono o ka lapaʻauʻia a me 70% - i loko o ka kēia mau kiʻina hana. ʻO kā mākou lehulehu o ka waiwai i loko o ke koko ma hope o ka malamaia 6-12 hola ma hope o 'ai, inu o ka papa. Ma ke kaʻina hana o ana Inc i nā maoli he bioavailability. Food maoli ka bioavailability i 40%.

ʻeleu waiwai 10% hoʻohuiʻia me ke koko nā polokina. E aho koke paka i loko, a komo iloko o ke koko-lolo ke'ākeʻakeʻa mai, ke keiki. A kekahi hapa o ka mea hele i loko o ka umauma o ka waiu.

Ua Ua metabolized i loko o ke ake, a ua wehewehe aku i ka papa kuhikuhiE metabolites elua ma ka Hoʻokolohua adrenoblokiruyuschey hana. Ke pūnao o ka lāʻau 'ohana isozyme CYP2D6.

Ka hapa-ola averages 3.5-7 hola. Ka lāʻau 'ua ole, kuu ma ke kino i hemodialysis.

Plural metabolites i noho i loko o nā mea maʻi me ka CC 5 ml / min., A i loko o keia hihia, kona Hoʻokolohua-adrenoceptor wahi hope, aole ia e hoʻonui.

Ke bioavailability hoʻomāhuahuaʻoe i ka maʻi ake cirrhosis. Ua i hoemiia ka huinaʻae.

"Metozok": nāʻikepili no ka hoʻohana

E hoike aku nei au i keia la hoomalolo relieves tachycardia, emi cardiacʻeha a me ka stabilizes ola. Nāʻikepili no ka lozenges mea hypertension, naau hoʻokō 'ole', a ma ka maʻi palapala, aia i loko o ka uku ke kahua. Ma ka hope Ina, i ka lāʻau ua? Aeiiaiaoaony e hoʻohana a me nā 'ano o ka luna' manao.

I hoakaka ia no ka cardiac ischemia lapaau "Metozok". Nāʻikepili ana ma ka ho'āhewa wale 'o ka angina (i loko o ka hale lio palapala) hoemi make a me ka emi ka likelihood o ka hou-infarction, ka hahai huʻi maʻiʻaʻai.

Ka lāʻau 'Ua pono no ka naau e hemahema kino pāpana, supraventricular tachycardia ka wā i hiki mai, e emi i ke alapine (frequency) o ke contraction o nā ventricles i atrial fibrillation a me ka ventricular arrhythmia.

Ka lāʻau 'He mana no ooieoeiiaeuiuo kāna hana o ka naau, i mea pu ma ka loa tachycardia. Ua Ua pinepine hoʻohana no ka migraine Kāohiʻana. Ua Ua waiho e loaa i ka lāʻau "Mezotok" nāʻikepili. Ke kūkākūkā i kēia e kālele ana ma luna o contraindications.

Contraindications i ka hoʻohana 'ana o

Ma kekahi hihia i papaia, e lawe i ka lāʻau ma luna o lākou iho me ke kauka o ka kuhikuhi. Papa ka mea, i koi 'ia ma cardiogenic hawewe a door-blockade II-III oolea. Mai hana koʻi i loko o ka sinoatrial aeie a me ka maʻi sinus maʻi pale. Ua lawelawe 'ana i ka Ban hoʻohana bradycardia (50 make. / Min) naau ole i ka huʻi a me ka maʻi decompensated. Contraindicated "Metozok" (mea hoʻohana wehewehe i oi au mamuli o ka noi ana o nā hiʻona a pau o ka medicament) no ka hypotension, myocardial infarction, Aia i loko o ka huʻi kahua o ka? Acaeoey, loa asthma, feohromotsite, ka haunaele o kaʻike ākea holo. Ikaika i ka manao ole i ka hui pu iho i ka huaale me Mao nā mea kūpale a me intravenous injections "Verapamil".

Ia mea,ʻaʻole e pono e hoʻohana i ka lapaau ana i na keiki, o kona mau makahiki i ole i umikumamawalu makahiki o ka makahiki, i breastfeeding, kanaka me ka deficiency a me ka lactose intolerance, e like me malabsorption maʻi pale, hypersensitivity e Hoʻokolohua-blockers, me metoprolol i.

Kaiapuni hoakaka ia medicament ka wā mimikō, au degere af-hihia a me Prinzmetal angina. ʻeleu maoli E i metabolic acidosis, he maʻi me ka bronchial asthma a me ka pulmonary maʻi, ake a me kaʻaʻa puʻuwai kahua. ʻaneʻane i hoakaka laau no myasthenia, feohromotsite, hyperthyroidism, kaumaha, psoriasis, malfunctions i loko o kaʻike ākea holo, i hāpai keiki, a me nā kūpuna.

Lapaʻau hookolokolo ma hapai wahine i ka aoao o ka lāʻau i ua hana. Aia ka hoi oleʻikepili ma o ka nui o ka anal o ka lāʻau i loko o ka umauma o ka waiu. No laila, i ka hanau keiki ana, a lactation papa ma mua i ka pono, e nīnau aku i ke kauka.

"Metozok": kauoha no ka hoʻohana

Reviews o kekahi hoʻomanawanui iki mai hōʻike i ka lāʻau hiki iʻaoʻao 'ole i loko o ka palapala o ka luhi. He nolaila, nui e hahai i ka rula, a loaa i ka paipai mahele lāʻau. Inā ke kauka ua oleʻOhi hana pākahi, oe e inu i ka Classic hihia Akala a "Metozok". Na Ke Kumu no ka hoʻohana ia kekahi e hoʻohana i ka lāʻau, hoʻokahi nō ka lā i loko o ke kakahiaka, ka nānā 'ana i ka palaoa. Dragees ka mea, i mama, a holoi iho la i kekahi wai iki me. I mea e pale aku bradycardia, i ka mahele lāʻau o ka lapaʻauʻia ua i nā mahuahua.

Ma ke alo o ka angina a me ka hypertension, lapaʻau ua hoʻomaka 'ia me 50 mg no ka lā. Ināʻaʻole i ke kanawai i loaʻa, Ua hoʻomāhuahuaʻoe i ka kela la i keia mahele lāʻau i 100-200 mg / lā, a me ka hypertension - i loko o kekahi mau hihia - Inc hoʻokō kekahi antihypertensive ka lapaʻauʻia.

No ka poʻe me ka maʻi naau hoʻokō 'ole' o ke kūlana II e like me NYHA Mea Maluna, me ka huʻi kahua no ka eono mahina, a me ka mea hou i loko o lapaau ma luna o ka hope lā he umikumamaha, nae ka loiloi mua mahele lāʻau o 25 mg koke i ka lā. Mau pule ma hope, ina e pono ai kela la i keia mahele lāʻau mahuahua i 50 mg, a laila, ma hope o elua hou pule, - mai i 100 mg, a ma ka ia manawa (14 lā) Ua mahuahua i 200 mg.

A lohe o III-IV maʻi congestive naʻau e hemahema, ua hoʻokumu pū iapaau ana me ke kaha o 12,5 mg hookahi i ka lā, a ma hope wale nō nā pule o ka helu mahuahua i 25 mg, a no laila, ma luna o - a hiki i ka i kā mākou-kela la i keia mahele lāʻau o ka 200 mg. Me keiaʻike, i loko o nā mea maʻi me ka hoomahuahua i loko o ka pākōlea mahele lāʻau e ia ma lalo o ke kokoke loa 'inikua hooponopono, mai ke ano e worsen i loko o kekahi nā mea maʻi.

Pili i ka lāʻau ma hope o ka puana Kāohiʻana o myocardial infarction a me ka naau hoʻokō 'ole' ana i loko o ka pākōlea kela la i keia mahele lāʻau o ka 100 mg.

Nā mea maʻi me ka ooieoeiiaeuiuo kāna hana o ka naau, ma ka a he mea no hoi he tachycardia, he lāʻau lapaʻau hoakaka 50 mg no ka lā. Inā pono, na kela la i keia mahele lāʻau mahuahua i 200 mg.

E pale ai migraine lāʻau ua? Aeiiaiaoaony e inu ma 100-200 mg no ka lā.

Mai hoʻomaʻa i ka pākōlea mahele lāʻau o ka kūpuna a me nā mea maʻi me kaʻaʻa puʻuwai hoʻokō 'ole' e noho ana ma hemodialysis.

akepaa mai loli i ka hoʻopau o ka metoprolol mai ke kino, no laila, i loko o keia hihia, i ka manawa o ka iapaau ana ua like pākōlea mahele lāʻau, nānā 'ole o ka hoʻomanawanui ka kulana.

overdose

Ua e e me ka mālama nui a wale ma lalo o kauka mau kauoha, e lawe huaale "Metozok". Alakaʻi ho'ākāka i nā contraindications ma i ka? Eaia o ka lāʻau mea,ʻaʻole hiki. Mau loea, Ua kuapo i 'ole-kaʻaeʻana i nā rula o nā māhele, a hookipa kānāwai overdosing, i ua pu ma ka ventricular extrasystole a me ka tachycardia, he manao o ka naau i loko o ke poo, na lima a me na wawae, e like me ka nui mahuahua i loko o ke koko,.

Lapaʻau ua lawe mai ma intravenous injections o Alpha-blockers a me Hoʻokolohua-blockers a.

ʻaoʻao waiwai

I oleloia, ma kekahi hihia, oiai e lawe i ka lāʻau, "Mezotok" e 'ikeʻaoʻao loa. E like me ke ahonui, ka mea i lilo ia i ala i loko o ke koko,, mahuahua naau ana, ventricular fibrillation, cardiac arrhythmia, a me ka bradycardia kardialgiya.

Ma ka hapa o ka Central ko mākou hopohopo System pōniuniu hiki e malama, ka unconscious manao o ka makau, uunu nui, hiamoe haunaele, headache, Muscle cramps, tremors, cerebral hemorrhage, paresthesia.

No nā maʻi puʻuwaiʻaoʻao, i poe lunakanawai no ma ka hōʻike manaʻo o nā kauka, a lākou nā mea maʻi i symptoms e like me haikea ili, ischemia o ka ili, i loko o ka wahi o ka ka pahu kui, allergies, necrosis, pehu pala ma ka ili o ka'aʻaʻa ma hope o ka hooponopono ana o subcutaneous injections.

I Ina o kaʻaoʻao 'ole, ka' Aha i hoaka ae i ka lāʻau "Metozok" manual. Analogs o keia k, e kōkuaʻoe koho i ka hana maikaʻi kauka.

Cautions

He nui loa i loko o ke kauoha o ka lāʻau "Metozok" nāʻikepili. Analogs i hoʻohana 'ia e hana i kēia mau maʻi i ole pela pohihihi keia. Lākou kaʻohiʻana i hoʻomalu, malama ke kālailaiʻana i keʻano o ka hoomanawanui, ma ka hanana i "Mezotok" no kekahi kumu i ole pono.

Ma ka iapaau ana e e pili loa ua hoʻonānā no nā hoailona o ECG, ke koko,, ke koko holo i loko o ka lima a me ka wawae, e like me cardiac auaiaea.

Ma nā mea maʻi me ka arterial hypertension a me ka congestive naʻau 'ole, ka mea, ua pono e malama i systolic ke koko, ma 30-40 mm o Hg. Art.

A hiki aku i ka mea ulu i loko o ke koko,, i ukali ia e symptoms o tachycardia a bradycardia, i kekahi manawa, aia nō ka hoʻohuikau 'o cardiac pāpana. Ma keia kulana, lapaʻau me "Metozok" (e manual ao mai e pili ana i hiki 'oleʻaoʻao) e e hoʻi i kāpiliʻia. E pale haumāna emi i loko o ke koko, ma hope o withdrawal o ka lāʻau, i ka mahele lāʻau ua i nā hoemi, o ka oi aku ina ua he hooloihi ae i infusion, drip a me ka hoʻomau 'ana i waiho ai i ka hoʻomanawanui ina ua hoemi ia i ka waiwai o 70-80 mm o Hg ka'aloʻahiʻa. Art.

I ka poʻeʻelemākule kanaka i ka helu o adrenergic receptors, i pakahi aku la ia i ka susceptible phenylephrine emi iho. I ka huli, monoamine oxidase nā mea kūpale, mahuahua ka compressing kanawai o ka sympathomimetic, hoʻonāukiuki ka eha ma ke poo, arrhythmia, ka luaʻi reflex, hypertensive hoʻoponopono ulia. E like me ka hopena, e hoomanawanui i ka hoʻohana monoamine oxidase nā mea kūpale, no ka 2-3 lā emi ka helu o sympathomimetics.

I ka manawa, kauka mai e waiho aku i ka papa Inc o ka hoʻopōʻino hana, a ua muli ma ka naoh māmā - nā ka noʻonoʻo a me ka physiological.

Me ka lōʻihi mālama nui e inu papa kanaka e loaa ana mai ka hakuʻala mai, a me ka kūpuna. Ka lāʻau 'E ole e lawe ia no na keiki ma lalo o umikumamawalu makahiki o ka makahiki ma muli o ka nele o ka ike ana o kona waiwai.

Ka lāʻau 'Ua hookuu mai keʻena kūʻai lāʻau lapaʻau pololei ma kuhikuhi.

Analogs medicament

He aha ina "Metozok" e pono ai no kekahi mau kumu? Analogs hiki mau ke loaʻa ma ka hale kūʻai lāʻau lapaʻau. Ka mea, i kēia nui ka iaʻeleu waiwai, a ma keia aoao pili i ke kino. Mau lapaʻauʻia nā:

• "Betalok".
• "Serdol".
• "Egilok C".
• "Vazokardin retard."
• "Metoprolol".
• "Korvitol 50".
• "Metokard".
• "Emzok".
• "Atenolol".
• "Lidalok".

Mau a me nā pani "Metozok" analogues i ua ana hoʻohana ma o ka iapaau ana o ka mea'ōnaehana mānowai koko ka maʻi. All kālā noi aku i ka hookokoke nui, a me ka mea hiki ole ke ia ma luna o lākou iho, me ke kauka o ka kuhikuhi.

e hoike

Awina "Metozok 'lākiō i ka puleʻAmelika, maikaʻi. People aku nei au i ka mea i oluolu i ka inu (ka paipai mahele lāʻau mea - i kekahi papa o ka lā). Lakou kamailio ana ia i ka manaʻoi kanawai. He nui nā mea maʻi e olelo aku nei ia ma hope o inu hoʻi poina e pili ana i ka eha i loko o koʻu naʻau.

Akamai i loko o ke kula o ka lapaau Ua hoi ikaika ka hoolea i ke huaale "Metozok". Reviews o ka lapaau hōʻike ana i ka lāʻau 'mea pono a me ka maluhia, no laila ka mea, ua pinepine i hoakaka ia ma ka cardiologists no lākou nā mea maʻi. Poe akamai i aku nei au ia i lapaau i ka papa kuhikuhiE mea - e koho i ka laʻau heluna akau, i ole oe e 'ikeʻaoʻao' ole e like me ka luhi, nausea, ka luaʻi, a diarrhea.