Ka lāʻau "Pentas": aʻo no ka hoʻohana, analogs a me nā hōʻike manaʻo

Ma kekahi mahele lāʻau o ka hoakaka ia ka lapaʻauʻia "Pentas"? Na Ke Kumu no ka hoʻohana, a me nā hōʻike manaʻo o ka lāʻau i ho'ākāka 'ia ma lalo nei. Nō hoʻi i loko o nā pono hana 'atikala hoʻolako' ike e pili ana i na ano o ke kala ana o ka lāʻau a me kona waiwai.

I ka haku mele 'ana, shape medicament

He nui na ano o ka kala noʻonoʻo laau. E hoʻonoho iā lākou i kēia manawa.

E hoomakaukau ai "pentasil" - papa (500 mg, 100 mg) hooloihi ae i hana. Ka mea, ua keʻokeʻo me ka grayish tinge, e like me loʻi lehulehu o ka malamalama eleele, i ka pololei a kinona, me Valium, bevel a me ka palapala ma na aoao elua.

Kaʻeleu hehee ai o keia ka lapaʻauʻia ka mesalazine. Nō hoʻi i nā mea i loko o ka palapala o ka AEeOEXAaI nā mea hoʻohui povidone, ethylcellulose, makanekiuma stearate, talc, a me ka microcrystalline kelulose.

Ma ke kuai ana o ka lāʻau "Pentas" (papa), he Hawaii photo no i ua hōʻike i ka 'atikala ua lako ma ka blister he huihui' ana i loko o ka pepa cartons.

Ua E hoi e hoʻomaopopo i ke kumuhana medicament hiki ke kuai i loko o ka palapala o suppositories, malama aku-hoʻokuʻu granules a me rectal mai paha.

Pharmacology lapaau

He aha mea i ka laau no ka "Pentas"? Na Ke Kumu no ka hoʻohana hākālia nō i keia Agena me Anati-hoʻoʻino hana, a hoʻohana 'ia no ka hana ulcerative colitis a me Crohn ka maʻi.

Anati-hoʻoʻino waiwai o ka lāʻau hoike wale no kūloko ana. Keia hana ua kena ae la ia e hoʻololi kemikala o leukotrienes a me prostaglandins, e like me ka inhibition o lipoxygenase ha awina (neutrophil). Eia kekahi, o ka mea kökua ka mea hiki ke retard i ka secretion o immunoglobulin ma lymphocytes a me ka inhibit degranulation, a me ka phagocytosis o neutrophil Polenekia.

No gastrointestinal konohiki

Ka medicament "pentasil" (i ka papa), ka haku mele 'ana o ka i i hōʻike mai iā ia ma luna, ho'āʻoʻia hai antibacterial hana ku e kekahi cocci a me Escherichia coli. No hoi, ka mea, mai ka antioxidant hookoia no i kona waiwai, e nakinaki i kaʻeleu waiwai me ka noa radicals (oxygen) a me ka luku ia.

Pololei o keia mea paahana nui ho'ēmi i kā ka pilikia o ka relapse ma Crohn ka maʻi, a me kanaka me ka ileitis (me ka lōʻihi maʻi lōʻihi like 'ole).

I ka rula o ka hana ana o iaeoaeuiiai eiiieaena e

Pehea ke ano o ka lāʻau "Pentas"? Na Ke Kumu ma ka noi hoʻike i ka pākōlea kanawai o ka lāʻau i koke ma hope o topical mesalazine hui 'ana me ka intestinal mucosa.

Ma hope o ka lawe una papa 'o ia hoʻi koke disintegrates ma microgranules i hana e like kaawale ano, a malama akuʻeleu waiwai kala - mesalazine. Ua 'oi aku ka glamor lāʻau no ma waena o 12- e rectum i nā mea a pau pH loina.

Pharmacokinetics ano

Pehea i ke omo o ka lāʻau "Pentas"? Na Ke Kumu no ka hoʻohanaʻana i nā hōʻike i microgranules o disintegrated papa 12 hiki i ka duodenum ma ka mua he 60 minuke.

Kahi o 30-50% o ka ke kemu laʻau heluna o ka lāʻau i loko o ka uuku liʻiliʻi. Kamaʻilio mesalazine me ka wai koko nā polokina ka 43% a me kaʻakika N-acetyl-kumamalima-aminosalicylic - 73-85%.

Mesalazine a me kona nā mea loaʻa mai i komo iloko o ka BBB. Huina lāʻau waiwai i hoike wale ia ka hoʻohana 'ana kiʻekiʻe nā māhele (ma kahi o 1500 mg no ka lā).

Acetylation mesalazine, ua waihoia ma ka intestinal mucosa a me ka akepaʻa. Keia waiwai ua loko mai o ka mimi, umauma ka waiu a me ka feces.

Nāʻikepili no ka hoʻohana o nā lāʻau

Ma kekahi mau hihia, ka lapaʻauʻia i ke hōʻike "Pentas" (papa)? House kilo'ōlelo aku nei au i ka lāʻau hanaʻia pono ia:

• ulcerative colitis;
• Crohn ka maʻi.

Bans ka hoʻohana o ka lāʻau

Ma lalo o ka hiki ole ana no keia hana i kahi mea paahana e like me "Pentas"? Na Ke Kumu (papa a me nā ano o ka ai 'i ka ia contraindications) i mai nei ka mea i kēia manaʻo pāpā o:

• hemorrhagic diathesis;
• koko maʻi;
• lactation;
• Digestive'āpana ulcers;
• ka hope 2-5 pule o ka hāpai keiki;
• ka nele o ka monakō koko-6-posapahate dehydrogenase;
• i ka makahiki o ka elua;
• loaʻaʻa puʻuwai ole;
• hypersensitivity i konohiki waiwai;
• loa hepatic insufficiency.

Special malama E e noʻonoʻo i ka lāʻau ia i loko o ka trimester mua o ka hāpai keiki, e like me ka pono i ake a me nā konāhua 'ole.

Medicament "Pentas": kauoha no ka hoʻohana

Koho i ka laʻau heluna kino o ka lāʻau hilinaʻi nui ma luna o ka IIeEeAIEUAA o ka papa kuhikuhiE pathologic kaʻina hana, e like me ka lōʻihi o intestinal lesions.

Suppositories "pentasil" a me ka wehe i lawelawe ma ka distalʻano o ka maʻi (proctosigmoiditis). I ka Ia manawa ekolu ihoiho i hoʻohana i ka lā o ka 500 mg.

Pehea e koi 'ia ke ku una ha ka lapaʻauʻia "Pentas" (papa)? Na Ke Kumu no ka hoʻohana hākālia nō i kēiaʻano o ka lāʻau 'ua pono, he pono ole ano o ka maʻi wale no. No ka mea Kāohiʻana o relapses ma Crohn ka maʻi i ka medicament ua noi ia, eha manawa i ka lā (1 g. Mesalazine). E pili ana i ka Kāohiʻana o ka relapse o UC, ma keia hihia, i ka lāʻau 'ua hoakaka ia,ʻekolu manawa i ka lā 500 mg.

Ma ka exacerbation o ka maʻi papa o ka iapaau ana, e mau no ka 8-12 pule. I ka Ia manawa i kēlā lā e lawe 400-800 mg o ka lāʻau (ekolu manawa i kela la).

I ka loa mai ke hoonui i ka kela la i keia laʻau heluna o 3-4 g.

Papa "pentasil" E kaʻoi loa e lawe 'ana ma hope o kaʻai, wai'uī maʻamau ka wai.

Hana ma-ke ano

Ma kekahi mau hihia, o ka lāʻau i ka ninau o ke kēiaʻaoʻao ole:

• stomatitis, tremor o mau lala, maloo waha, pōniuniu, nausea, e kaumaha naʻau i loko;
• lilo o ka ikaika loa ka makemake, e manao ana palpitations, heartburn, pokole o ka hanu iloko o physical haʻawina, ka luaʻi;
• hematuria, diarrhea maʻi pale, tachycardia, hepatitis, umauma eha;
• ulu ake nā'ūhū, ke koko, fluctuations, pancreatitis, polyneuropathy;
• crystalluria, tinnitus, proteinuria (kumuʻiʻo excretion), migraine headaches;
• oliguria, leukopenia, anuria (wa e kaawale aku o ka urination), thrombocytopenia, ho okumu nephrotic maʻi pale ;
• hypoprothrombinemia, agranulocytosis, eosinophilia, anaemia.

Ua E hoi e hoʻomaopopo i kaʻai ana o keia k i loko o ka hoʻomanawanui hiki e malama: olisgospermiya, alopecia, photosensitivity, nawaliwali i mau lala, lupus-e like maʻi pale, hoemiia? Iecaianoaaiiie o lachrymal loli, parotitis.

Overdose o ka ai '

Overdose epa a me na mea e hana loa sleepiness, nausea, gastralgia, ka luaʻi a me ka nawaliwali ma ke kino. E hoʻopau i kēia mau symptoms āpono ke ake gastric lavage like hoʻi me ka hookohu o laxatives lapaʻauʻia a me posindromnoy Inc.

lāʻau hana kūleʻa

Ka medicament "pentasil" Ua hiki, e 'ūlōlohi i ka uku o ke omo o ka cyanocobalamin. Mesalazine kekahi maoli ka ka hoʻokōʻana o uricosuric Luna (me blockers o omo secretion).

Mākou E hoi e hoailona oukou i kaʻeleu lāʻau, piʻi pū ulzerogennosti glucocorticosteroids ho'ēmi i kā ke kanawai o ka rifampicin a me ka hoʻokāʻoi aʻe ana i ka kaʻawahia o methotrexate ka lawe hypoglycemic hopena ma sulfonylurea nā mea loaʻa, spironolactone, furosemide a me sulfonamides.

i kekahi Mau 'ike

Ma ke komo ana o ka hookahi mahele lāʻau o ka mesalazine ka mea, ua waiho i ka lawe ia pu me ka hahai ana paha i loko o ka wā e hiki mai kokoke loa. Inā ka mea i nalowale he mau nā māhele, 'oe e ike koke nīnau i kou kauka. Ua ua hiki ole, e hooki aku i hana maikaʻiʻole ma luna o lākou iho.

I kekahi manawa, i ke kāʻei kua o ka hōʻike 'ana no konohiki i loko o nā mea maʻi malama mimi kohu. A me ka hui' nā aniani kaulona ma yellow-alani hue.

Ma ka iapaau ana o ka mesalazine pono a eia i 'inikua hooponopono maluna o ka hana o kaʻaʻa puʻuwai oihana o ka hoʻomanawanui. Nō hoʻi, i ka Ikepili o ka hoʻomanawanui ka mimi a me ke koko e e mau (ma ke ala o ka Inc, e like me ma hope o kona paa).

Ua hoomahuahua ia ka pahiki o ka hanana o adverse reactions i loko o nā mea maʻi e loaa ana keia k i loko o ka poe i "na mea acetylators".

Me ka hooulu ana o ka huʻi maʻi pale o intolerance i ka hana 'Oponopono hoomakaukau "Pentas" koke kahuli.

Similar ai 'a me ka consumer hōʻike manaʻo

Anei oe ike o ka hiki mea e noʻonoʻo e puku i ka lapaʻauʻia? Ma keia oe e hoʻomaopopo i ka hele kauka. E like me ka mau rula, i analogues o kēia mea paahana nā na kēia mau ai ': "Mesakol", "Salozinal" "Salofalk", "Mezavant", "Mesalazin" "Asacol".

He aha kanaka i ka i ana e pili ana i keia mea paahana, nā mea kūʻai mai? E like me kā lākou pane, i mai la medicament mea he lahui pono ka lāʻau i ke kuai hiki i kekahi hale kūʻai lāʻau lapaʻau. E hoomanawanui i koi ia mesalazine ka loa maikai hoike mai ai ia ia iho i loko o ole wale lapaʻau akā, i loko o Kāohiʻana o Crohn ka maʻi a me ka ulcerative colitis.