Ka lāʻau "Remicade": aʻo no ka hoʻohana 'ana, maoli

Ka pono o ia hoʻi, "Remicade"? Na Ke Kumu no ka hoʻohana 'ana, ahonui hōʻike manaʻo o kēia lapaau, e e hōʻike mai iā ia ma lalo nei. Nō hoʻi i loko o kēia 'atikala, oe e aʻo ana i loko o kekahi hihia, i koi' ia i ka lāʻau, ike ia he mea contraindications a me adverse loa, a eiiiiiaiou i kekahi hapa o ka ia, a no laila, ma luna o.

Palapala, haku mele 'ana

E hoomakaukau ai "Remicade" ua hoopuka ia i loko o ka palapala o ka lyophilized pauka manao ia no ka makaukau o ka infusion pāʻoihana. Kaʻeleu 'Oponopono o ka lāʻau mea infliximab. Ua hoi he mau eiiiiiaiou like polysorbate 80, paʻakai hydrogen posapahate dihydrate, sucrose a me ka monohydrate paʻakai dihydrogen posapahate.

Key waiwai

He aha ka ka lapaau "Remicade"? Na Ke Kumu no ka ho ohana i hākālia nō i ia mea he immunosuppressive Agena.

Puka i loko o ka kino, i ka lāʻau hoʻomaka e pāʻani aku me ka wailana a me ka transmembrane ano o kaʻeho necrosis, alpha (TNFα), hoemi kā lākou hanana hulina ma ka ho okumu ana o ka hale lio eiiieaena.

Research poe akamai i paipai i kaʻeleu lāʻau waiwai ho'ēmi i kā ke kelepona hele infiltration (hoʻoʻino), a me ka helu o ka hoʻoʻino hōʻailona ma ka hoʻohuli ai i nā wahi o ka naʻau liʻiliʻi. Pela ka mea, he 'ano kokololio hoola ana o ka mucousʻili lahilahi.

Pharmacokinetics

He aha nō ka pharmacokinetic kiko'î a ua lapaau "Remicade"? Note, manaʻo moku'āina i ka hookahi intravenous ka pahu kui o ka infliximab i loko o ka nui o ka mai i ka 20 mg / kg i ukali ia e kekahi hapaʻauhau mahuahua i loko o kona i kā mākou lehulehu.

Hou noi o ka lāʻau kumu he hōʻemi iki hoʻomāhuahua oʻeleu waiwai i loko o ka lāʻau lapaʻau.

Aoao o ka hoʻopau o ka lāʻau i ole, ua hōʻike '.

nāʻikepili

No ka mea hana i ke kohoia lāʻau "Remicade"? I ka hana o keia ka lapaʻauʻia ua hoike mai ia ma ka mea i kēia hihia.

• Rheumatoid arthritis i loko o kaʻeleu palapala (ina ua ineffective malamaia lakou nei, e hoomanawanui i walaʻauʻana antiinflammatory ai '). Inc Ua lawe mai i loko o ka hui pu ana me "methotrexate". Keia hui malu pu ana apono 'no ka hoemi i ka hoailona o ka maʻi, e like me ka pono me ka hana ana o ka hui e like me ka a pau.
• Crohn ka maʻi i loko o kanaka makua nā mea maʻi. Ma keia hihia ka mea, e kokua i ka "Remicade"? Alakaʻi hākālia nō i Inc me keia la hoomalolo e e mālama 'ia ma ka hihia o ka intolerance a ineffectiveness, akā, no hoi me contraindications i ka maʻamau lāʻau. Ma kaʻike, "Remicade paipai 'ia ka hoʻopau o nā mea a pau maʻi symptoms, malama ana ke kala a me ka kokololio hoola ana o ka eha, fistula panina a me ka hoʻoikaika' ana i ka hoʻomanawanui ka kulana.
• Crohn ka maʻi i loko o adolescents. Iapaau ana me keia k ua lawe mai ma ka hihia o ka intolerance a ineffectiveness, akā, no hoi me contraindications i ka maʻamau noaia o Inc. Medicament "Remicade" ho'ēmi i kā symptoms a Kākoʻo kala ana, a hoonui ae i ka pono o ke ola o ke keiki hoʻomanawanui iki mai.
• Ulcerative colitis i loko o nā mākua. Uluwehi O "Remicade", i hōʻike manaʻo hōʻike ma lalo nei, ua lawelawe i loko o ka hanana iʻike mau Inc ua ineffective. Iapaau ana o keia Agena ho'ēmi i kā nā symptoms o ka maʻi, i ka intestinal mucosa hoola ana, ka ho'ēmiʻana a me abolition o GCS dosages. Ua E hoi e kaulana ia, ma hope paha o ka mea paahana eliminates i ka pono no ka haukapila iaʻu.
• Ulcerative colitis i loko o nā keiki. Iapaau ana me keia k i hoakaka ia no na keiki elemakule 6-18 makahiki, ina hoao ineffectiveʻike mau Inc.
• Ankylosing spondylitis (me ka maʻamau Inc inefficiency). E like me kaʻike, kōkua lapaau "Remicade"? Na Ke Kumu no ka hoʻohana mau moʻolelo i kēia mea paahana ho'ēmi i kā ka hoailona o ka mai, a hoonui ae i ka functioning o na ami.
• Psoriasis (me ka maʻamau Inc inefficiency). Like ma ka psoriasis e kōkua "Remicade"? House kilo'ōlelo aku nei au i keia k ho'ēmi i kā li nui i loko o kaʻili, a normalizes ke kaʻina o ka keratinocyte differentiation.
• Psoriatic arthritis (no ka maʻamau Inc inefficiency). Ka medicament "Remicade" lawelawe i loko o ka hui pu ana me "MTX" a me monotherapy me contraindications paha intolerance i ka hope. E like me ka hopena, i ka lapaau hoemiia na symptoms o arthritis, e hoomanawanui i holomua ooieoeiiaeuiiai haʻawina, e like me emi ka degere o radiographic Holomua ma psoriatic arthritis.

Contraindications

Lapaʻau "Remicade" i pāpā 'ia ka wā:

• loa infectious kaʻina (e laʻa me, sepsis, abscess, tuberculosis, opportunistic nā mea palahēhē) ;
• mahuahua pā lonoaʻili o ke hoʻomanawanui, e infliximab a murine nā polokina a me kekahi'ē aʻe eiiiiiaiou o ka lāʻau;
• ma lalo o ka makahiki o 6 makahiki (ulcerative colitis a me Crohn ka maʻi);
• hāpai keiki;
• naau ole;
• ma lalo o ka makahiki o nā makahiki 18;
• breastfeeding.

Uluwehi O "Remicade": olelo ao no ka hoʻohana. A me kahi e komo (ina i loko o ka haukapila wale)?

Nānā akula au i ka lapaʻauʻia ai e haawiia mai ma lalo o ka hooponopono ana o ka hoʻomalu (oa haukapila) ka mea i ka pono hana o kaʻike, a me ka holomua lapaau o ka maʻi ma luna wale nō.

Ka pāʻoihana Ua hoʻolauna dropwise intravenously no 120 minuke. Ka pākēneka E ole e oi aku mamua o 2 ml no minuke. Hoʻokō i kaʻina hana pono me ka hoʻohanaʻana i ka infusion nenoaiu.

Ke laʻau heluna o ka lāʻau hilinaʻi nui ma luna o ka hoike.

rheumatoid arthritis

Ma kaʻike, hana loiloi mua mahele lāʻau E e pili ana i 3 mg no kg. Ke medicament Ua lawelawe pinepine ae la oia ma 3-6 pule. A laila, hana ia kela mau mahina.

I ka hanana i ka pākōlea ia i ole, ua loaʻa, e noonoo pono i ka hoopau ana o Inc.

I hookuu i ka lāʻau 'o "Remicade" me rheumatoid arthritis lawelawe pu me ka "methotrexate".

ulcerative colitis

Ka loiloi mua laʻau heluna ia kaʻike, ka 5 mg no kg kino ke kaumaha. Ka hookahi mahele lāʻau o ka lāʻau 'ua lawelawe 3-6 pule ma hope. A laila, lawe mai nā'āpana hana e kela mau mahina.

Inā pono, hiki e mahuahua ai ka mahele lāʻau a hiki i 10 mg no kg. Ke kanawai o ka iapaau ana ua ana ike i loko o 14 pule. Ma ia hihia, ina ia mea ole, oe e hoʻomau lapaau.

psoriatic arthritis

Psoriatic arthritis lāʻau "Remicade" lawelawe i ka loiloi mua mahele lāʻau o ka 5 mg no kg. Ke medicament Ua lawelawe pinepine ae la oia ma 3-6 pule. A laila, hana ia kela 7-8 pule.

I koi 'ia ka lapaʻauʻia hiki ke hui me "methotrexate".

Crohn ka maʻi

Ma kaʻike, no nā mākua i hōʻike hookahi nā māhele o ka 5 mg no kg. Inā ka pākōlea hopena i ole, ua loaʻa ia no ka hala 2 pule, i ka lāʻau kahuli.

Inā he maikaʻi lāʻau hana, i ka i kēia manaʻo.

• Ke kākoʻo pāʻoihana Ua lawelawe i loko o ka hookahi mahele lāʻau like i loko o ka infusion mua, a ma hope o 3-6 pule hoʻohana hou 'ia. Ma hope iho o ia, e na injections kela mau mahina. Inā koi 'ia, hiki e mahuahua ai ka mahele lāʻau a hiki i 10 mg no kg.
• Ka lāʻau 'Ua lawelawe wale i relapses ināʻaʻole nō ma mua o 16 pule ma hope o ka hana mua.

Crohn ka maʻi i loko o kahi mau keiki liilii

Crohn lōpū ole loa i na keiki ma lalo o makahiki 18 komo ai i ka hoʻohana 'ana i ka loiloi mua mahele lāʻau o ka 5 mg no kg. Mahope injections pono e hana i 3-6 pule. A laila, i ka lapaʻauʻia ua hoʻohana 'ia o kela mau mahina ina kauoha ia, like me ka laʻau heluna o 10 mg no kg.

Nō kāu, i ka lāʻau ua hui me immunomodulators 6-mercaptopurine, "azathioprine" a me "methotrexate". Inā ka pākōlea hopena i ole, ua loaʻa (no ka 10-11 pule), ka hoʻohana 'ana i ka lāʻau' mea undesirable.

Crohn ka maʻi ua pu ma fistula

A hookahi mahele lāʻau o ka lāʻau i kaʻike, he 5 mg no kg (i loko o nā mākua). Ka lapaʻauʻia hoʻohana hou 'ia ma hope o 3-6 pule. Inā ka pākōlea kanawai ma hope o 3 injections ua i malama, alaila, hoi kanaka mea ole.

Me ka maikaʻi hopena o ka lāʻau, i ka i kēia manaʻo.

• reintroduction hope 3-6 pule, a laila, na nā mahina;
• ka medicament ua lawelawe i relapse ina mea i emi o 16 pule.

ankylosing spondylitis

E like me kaʻike, lāʻau i "Remicade"? Na Ke Kumu no ka hana Hawaii i loko o kēia maʻi loiloi mua laʻau heluna o ka lāʻau e e 5 mg no kg. Ma hope iho o kēia, ua lawelawe ma hope 3-6 pule o ka lāʻau.

Iapaau ana e ole e hoomauia ina, i loko o eono pule i ke kanawai mea,ʻaʻole kekahi '.

psoriasis

Ma ka iapaau ana o ka psoriasis ho mahele lāʻau mea 5 mg lāʻau no kg. Hou noi o ka medicament lawelawe ma hope 3-6 pule, a laila, - koke iho o kela mea keia ewalu pule.

Kaʻina hana no ka makaukau o ka infusion pāʻoihana

e hoomakaukau i ke kākoʻo pāʻoihana e like penei:

• Ua ho omaulia i ke ka mahele lāʻau a me ka helu o nā hue.
• Ka lāʻau pauka i mea hoʻoheheʻe i loko o 10 ml o ka wai a me ka hoʻohana 'o ka' ohe. E hana i kēia, e lawe aku oe i ka'ūheheʻe hue chap (ea), a holoi i ka pani me ka waiʻona. Ka puka o ua hookomoia ma kona konu, a ua alakaʻi i ka loli ma ka pa.
• Ke kākoʻo pāʻoihana Ua pono, hookonokono lakou (rotational ana) a hiki i ka lepo ua mea hoʻoheheʻe. Uluwehi O wai e e kekahi colorless paha melemele tint. Inā i ka hoʻohuihui hue hua i hanaia, ia mea pono e hookomo ua i ka pāʻoihana o 5 minuke. Ka hope loa laʻau heluna pepa paha e noho translucent ke olonā i (particles).
• Ka huina o ka leo o ka lapaʻauʻia ua like ia 0,9% koloriside (250 ml) o ka paʻakai pāʻoihana. No keia mea i ka hoomakaukau wai a ua hou a hiki i ka hue, a iloko ona i kakauia mua paʻakai koloriside. He mau eiiiiiaiou e ho'ōla loa i hui pūʻia.
• Introduction o ka la hoomalolo ua lawe mai i hope ma mua o 3 hola ma hope o ko lakou hoomakaukau ana no ka lāʻau pāʻoihana.

Ua Ua papaia e komo i ka lāʻau a me nā Luna ma ka ia kahua. Inā he mau haole mea a opaque (particles) i loko o ka pāʻoihana, ka mea, ua i paipai.

Ua hanaʻole nui o ka lāʻau i ka e hoʻohana 'ia.

ʻaoʻao waiwai

I ka hoʻohana 'ana i ka medicament, ke kēiaʻaoʻao reactions:

• kaumaha, apathy, mahuahua uunu nui, pōniuniu, somnolence, nervousness, amnesia, psychosis, headache;
• pulmonary edema, sinusitis, bronchoconstriction, dyspnea, allergic reactions, pneumonia, epistaxis, bronchitis, pleuritis;
• conjunctivitis, keratoconjunctivitis, endophthalmitis;
• nani a me ka urinary'āpana nā mea palahēhē;
• kai, mai ka pioloke o kaʻike ākea holo, bradycardia, ecchymosis, hematoma, vascular spasms, syncope, palpitations, cyanosis, petechiae, arrhythmia;
• thrombocytopenia, anaemia, neytrotsitopeniya, leykotsitopeniya, lymphopenia, lymphadenopathy, lymphocytosis;
• cheilitis, constipation, cholecystitis, reflux, diverticulitis, diarrhea, nausea, indigestion, hoʻopōʻino ake ho'āʻo;
• ili poʻe noʻonoʻoʻole, malooʻili, alopecia, seborrhea, ka ohane, abrasions, poʻe noʻonoʻoʻole, sweating mahuahua, dermatitis, fungal, warts, hyperkeratosis, erysipelas, he 'aʻe' o ka ili pigmentation, bullous pele.

Reviews o ka la hoomalolo

Ano, e ike ana i ka hoʻohana 'ana i ka lāʻau "Remicade". Na Ke Kumu no ka hoʻohana ana i ka lāʻau 'i, ua ho'ākāka' ia ma luna.

Ma ka hapanui o hihia, noʻonoʻo i ka mea e Makuakane me ka hana. No laila, i kou manaʻo, mai nā mea maʻi i loaʻa ka hapanui maikaʻi. People ka poe i hana i kēia pāʻoihana, hōʻike i ma hope o ua aneane loa hele i ka ka pahu kui o ka eha. Naʻe, kekahi nā mea maʻi i makau i kaukaʻi, ka mea hiki ke kumu.