Nā wānana - nā aha? Nā mea'olu'olu a me nā antidepressants

Hoikehonua, "frantic" iki mai o ke ola, he kahawai pau ole o ka 'ike i ke kanaka pono, e lawelawe ma ka kela la i keia manawa, e like me na mea e ae, ka hapanui o ia io aʻe alakai ai i ka mea ana i ke kino a me ka naau hiki ole ke ku. Kanikani'āʻula a me ka stress, malfunction a me ka launa pu, ua pinepine AOON, a me ka pinepine ka hanu mai ma ka ai 'ole' ē aʻe potent waiwai, e ho'ōla alakai i na luna 'maʻi, e like me maʻi luhi maʻi pale (CFS) a me kaʻokoʻa kaumaha. E like me na Time] o nā kānaka kālailai o ka 'inikua kaumaha a hiki i ka 20 la makahiki o keia keneturia ma ka helu o nā hihiaʻoi nā luna o ka iwakalua kenekulia - infectious maʻi a me nā maʻi o ka mea'ōnaehana mānowai koko nenoaiu. Ma ka paio me ka depressive kāna hana, likeʻole ai 'ma nā ka nānā' ana ma luna o kona ano maoli, a kemikala eiiiiiaiou. Antidepressants - He aha ka mea? He aha ka mea e, a ina paha mau ai 'e hoola hoi lakou i kaumaha ole wale kōkua kona symptoms? He aha nō i ka pono a me keakea o na ai '? He 'atikala e ho'āʻo e, e olelo aku i kēia mau a me nā nīnau e pili ana i ka antidepressant hopena o ko lākou pono, a me ka hopena o? Eaia.

He aha ka mea?

E like me ka inoa hoʻohuʻu, antidepressants (i kapa timoleptikov) - he psychotropic ai 'i hana ku e depressive symptoms. Mahalo i kēia mau ai 'mahuahua ka iini a me ka excessive mea naʻau stress, listlessness a me ka lethargy, Kanikani'āʻula me ka nui loa hoemiia paha a hiki loa iʻa. Attributable i keia pae ana o ai 'i okoa nā loko o Nine Inch' ole a me ka haku mele 'ana, a me keʻano papa hana o ka hana.

Pehea 'aʻole ia hana?

E ka maka ia, Anati-depressants - ia mea: no ka make ana o ke kino a me kōkua kuʻi kanaka psyche. E ka nānā i ana i kēia mau ai 'hana. Ke kanaka lolo ninoieo o ka ai iiiaanoaa o neurons - ke aʻalolo keena, mau hana 'ikepili e loaa hou mai ma waena o lākou. No ka EYI o ka 'ike pono' ilepiliʻelele waiwai - neurotransmitters, penetrating ma ka slit i loko o ka synaptic makahiki ma waena o neurons. Hoikehonua, noiʻi kuhikuhi i oi aku mamua o 30 okoa neurotransmitters, akā, me ka ana a me ka papa o ke kaumaha i ka "pono" heluia, waleʻekolu o lākou: serotonin, noradrenaline (norepinephrine) a me ka dopamine. E like me ka noiʻi aeaiiua, kaumaha ia lŘlŘ ka wā o ka AaOIeIOUIeXAOAaIN o neurons i loko o ke kula he mea he nui laupaʻi ka ho'ēmiʻana o neurotransmitters. Kanawai o antidepressants ua nona e hoʻoulu ai i ka helu o ke pili uao a me ka normalization o ka biochemical koena o ka lolo.

A wahi moʻolelo

Ma mua o na lede i ka noonoo ana o Contemporary pūʻulu a me ke ano o antidepressants, pokole hōʻike i ka mōʻaukala o ko lākou loaʻa.

A hiki i ka hapalua like-iwakalua kenekulia, kaumaha a me kela neurotic aku ana me ka like symptoms, ua malamaia lakou me nā lāʻau lapaʻau hoomakaukau. E "kau i ka naʻau i loko" hoʻohana i kekahiʻano o ka pīhoihoi mele, i ka i nā caffeine, ginseng a me ka poeikohoia o ka opiates. "Soothe" jitters ho'āʻo bromine paʻakai a me na laau me ka nānā 'ana ma valerian. kekahi mauʻano o nā kino a me ka ohe. physiotherapy kona laulā i Ua loa haʻahaʻa no hoi ke hoʻohana 'ia.

I ke kakahiaka nui 50-ies o ka lāʻau "Promethazine" Ua hanaia e ka iwakalua kenekulia, Ua hoʻohana mua no anesthesia iʻoki kino. Pharmacologists Ua ho'āʻo e hōʻoi 'i ka inhibitory, a me ka inhibitory hopena o ka lāʻau, a me ka hopena i ka 1951 ua loaa "Chlorpromazine", i i lohe nui ia i loko o' inikua hana, hana maikaʻiʻole o ke kaumaha. I kēia lā, i kēia lāʻau 'ua ike ia "Chlorpromazine".

Ma ka hopena o 60-ies o ka hope kenekulia Hawaiian kauka, lechivshimi nā mea maʻi me ka tuberculosis, ua hoailono aku la ma kekahiʻano hanaʻaoʻao kanawai o kēia lāʻau 'like "Iproniazid". E hoomanawanui i ka loaa ana ia, ua kiʻekiʻe naʻau i loko. I nā mea hoomaka e e hoʻohana 'ia ma psychiatric me ka hana pono i tuberculosis, ia i kokua loa uuku. A puni ka ia manawa he German kanaka noiʻi Ronald paha loaa lāʻau "Imipramine".

E wehewehe ana o ka timoleptikov mua alakai aku ai i ka kokololio kūpono 'ana o ke pharmacological noiʻi i loko o kēia wahi, a me ka hana ana o ka hou ai', e hakakā i nā symptoms a me nā kumu o ke kaumaha.

kēia Mea Maluna

Ke kaumaha ma muli i ke ano o ka hookoia i ka hoʻohana ana o antidepressants i kaumahaʻia ma ka hoomanawanui, e puʻunaueʻia ka mea, penei:

Eia hou, aia no he Mea Maluna ma muli o ana i ke kanawai o antidepressants lakou aloha ia ka biochemical keʻano o ka hanaʻana i loko o ka kanaka kino:

• Tricyclic antidepressants - tricyclic timoanaleptiki.
• MAOIs - Monoamine oxidase nā mea kūpale:

- irreversible ( "tranylcypromine," "phenelzine");

- reversible ( "Pirazidol", "Moclobemide").

• SSRI - e wae serotonin reuptake nā mea kūpale;
• IOZSIN - serotonin reuptake nā mea kūpale a me noradrenaline;
• NaSSAs - noradrenergic a me kekahi serotonergic antidepressants.

Nō hoʻi, aia nō i ka helu o ka antidepressant ai 'i ole e wahi hiki i kekahi o kēia mau pūʻulu.

TCA: tricyclic antidepressants, aha ka ia?

Ai 'tricyclic pūʻulu e like me "Nortriptyline", "Imipramine" a me ka "Amiltriptilin" loaa ae nei i kona inoa, mai ka nń ku Triple kalapona apo hookahi. Mau antidepressant ai 'kōkua hoomahuahua i ka helu o ka lolo neurotransmitters e like me norepinephrine (noradrenaline) a me ka serotonin (hōmona o ka pomaikai). Kēia Ua loaʻa ma ka hoemi i ka nui o ka hoopau ana o ke aʻalolo keena - neurons.

Aie i ka mea i ma ka loaʻa mua o kēia mau ai 'i wahi e ole wale e pono neurotransmitters, he nui na kekahiʻaoʻao ona. Tricyclic antidepressants pūʻulu hiki i ka i kēiaʻaoʻao ole:

• lethargy;
• drowsiness;
• nausea;
• maloo waha;
• nawaliwali;
• pōniuniu;
• hoʻonui o ka naau kōmi - lāʻau ikiʻai wale;
• constipation;
• lalo potency a me ka libido;
• ka iini a me ka iini.

Mau ai 'i ana i hoakaka ia ma ke kauka i loko o ka wahi mua, no ka mea,ʻo ka loa? Anoee, a me ka waiwai o ko lākou pono i ua' ike nui.

MAOIs - Monoamine oxidase nā mea kūpale

E hoomakaukau ai "Iproniazid" wehe i kekahi o ka mea mua, e like me nā ai 'o keia pae, e like me "isocarboxazid," "tranylcypromine" inhibit monoamine oxidase'ūhū naoh, maluna olaila i loko o ke aʻalolo a hāʻule pahū wale. Manawa a hiki i kēia, i ka neurotransmitters mea i kuleana no mākou naʻau i loko, e like me serotonin, noradrenaline a me ka tyramine, ua i hoohioloia a me ka lohi accumulates ma o ka lolo.

Ka loa mau hoakaka antidepressants, MAOIs no atypical kaumaha, a me ka wā ai 'tricyclic pūʻulu i ole e hele mai, a i ole i ka mea i makemake ia. I ka pono o keia pae ana o ai 'o ka mea i ka mea, e ole i ka poi pu keiki, a ma ka mea ku ole, hoʻoulu ka noʻonoʻo' keʻano o ka hanaʻana.

Like pono me ka tricyclic ai ', MAOIs i koke ole hopena ma luna o ke kanaka - antidepressants keiki hele mai ana he mau pule ma hope o ka hoʻomaka' ana o ka hiki aku.

Aie i ka mea i Mao nā mea kūpale i nuiʻaoʻao 'ole (a me kekahi ma ka haiia pane koke me ka ai' no ka cough a me ka ho'ānoʻole ke anu, a hiki hoʻonāukiuki ola-na olelo hooweliweli e elevation o ke koko,) akā, no hoi, no ka ka mea 'anoʻoʻoleʻaʻai ka wā lawelawe i koi 'ia ai' kākaʻikahi, ka wā 'ē aʻe ohe. i ole kōkua.

e wae serotonin reuptake nā mea kūpale

Mākou hookolokolo aku la ia i ka pae ana o TCAs a me MAOIs - ia ka hapanui nei wehe a me ka maikaʻi-? Anoee ai '. Akā, i ka "kahiko" hanauna o antidepressants i ke kiʻekiʻe o UAIAaIN e oi laekahi 'ai' e aeie i ka hana o neurotransmitters,ʻaʻole a pau, akā, wale he hookahi - serotonin, pale kona nana e hoole hoʻokokōhi neurons. Kēia maoli o ka lehulehu a me ka mai i ka pākōlea hopena. E hoʻokomo ia mau laekahi SSRI ai 'e like me "fluoxetine", "sertraline", "Zoloft", "Paroxetine" a me na mea e ae. Ma keia pae ana o ai 'kaulana poʻeʻuʻukuʻaoʻao waiwai, a me ka mea, e ole ka nui o ka pili i ke kanaka kino.

Serotonin reuptake nā mea kūpale a me noradrenaline

Kēia mea he 'ano hou lāʻau, a e pili ana i ke kolu o ka hanauna antidepressants. Lākou e hoʻoili ana ka hana i loko o ka hapalua like 90-ies o XX kenekulia. Ai 'e like me "Cymbalta", "Effexor" aeie ka reuptake o ka serotonin mea,ʻaʻole wale nō, akā, i noripinefrina, akā, ai' e like me "Wellbutrin" a me ka "Zyban" pale aku i ka hoi ana mai o ka norepinephrine a me ka dopamine.

Uluwehi Oʻaoʻao waiwai i loko o kēia pūʻulu mea nui uuku ma mua o ka mea 'ē aʻe, a me ka mea i olelo ia, aole i weakly. Ma hope o ka loaa ana antidepressants, hana ma ka muli o ia nā mea kūpale me "duloxetine" a me ka "Bupropion", aole paha e ka hoomahuahua i loko o ke kaupaona a me na mea uuku dysfunction i loko o ka moe poepoe.

Noradrenergic a me ka hana i ho'ākāka 'serotonergic antidepressants - NaSSAs

Kekahi o ka Contemporary pūʻulu i NaSSA antidepressant ai 'e' ūlōlohi mai ana paha ka palemo i ka hopu ana o noradrenaline synapses o ke aʻalolo keena, ma laila mahuahua kona lehulehu. Na ai 'like "Remeron" "Lerivon" "Serzon" lawe mai wahi o serotonin receptors.

No ka lapaʻauʻia i loko o kēia pae malaila i mehana meaʻawaʻawa loaʻaoʻao 'ole e like me drowsiness, maloo waha, mahuahua ikaika loa ka makemake a me ka pili kaumaha o koʻu pomaikai ia. Hawaiian antidepressants o keia pae i wahi me kekahi nui pilikia.

Ma waho o ka kumu o nā pūʻulu antidepressants luna, ma laila nō i ka helu o ka ai 'i ole e wahi hiki i kekahi o lakou. Ka mea, oko i loko o nā Nine Inch haku mele 'ana a me kaʻano papa hana o ka hana. Kēia, no ka laʻana, ai 'e like me "Bupropion", "Hypericin", "Tianeptine", "Nefazodone" a he nui' ē aʻe.

'ano like ki ina hana like

I kēia lā, na poe akamai i mea increasingly hoʻohana no ka iapaau ana o ke kaumaha lapaʻauʻia i aloha ia neurotransmitters, aʻaʻole ma luna o neurotransmitters, akā, ma luna o ke ano o ka endocrine'ōnaehana, e like me ka mea adrenal glands, hypothalamus a me ka pituitary gland. Kekahi o kēia mau ai ', e like me "Aminoglutethimide" a me ka "ketoconazole" inhibit adrenal hōmona cortisol hoʻololi kemikala, akā, ka mea, i nuiʻaoʻao mau waiwai, a i hopena maikaʻi' ole ma o ka endocrine nenoaiu.

Ka lua o ka pūʻulu ua ana haawiia antalarmina mea loaʻa hakaka hui pu iho i ka maikaʻi ano a i tranquilizers a me antidepressants.

Ma waho aʻeo ia pharmacological lapaʻau o depressive Hawaii, e increasingly hoʻohana 'ana i kūpono e like me intermittent normobaric hypoxia a me ka plasmapheresis, malamalama Inc, e like me na mea e ae e ho'ēmi i symptoms a me amelioration o symptoms.

Pro a me ka Con

Ka hapa nui o ka poe i antidepressants,ʻae i ka mea i loa ka hoʻokō ai ', o ka oi aku ina e lawe lakou i ka mea ia manawa lawelawe' ia ma ka hoʻomalu papa o ka Inc. Ua hoʻomanaʻoʻia ai ia i ke hoonoho i mau ai 'a me kā lākou laʻau heluna he kauka, ma lalo o kona hooponopono ana a me ka i, e lawe ia lakou. Mai manaʻo no kekahi manawa hou. E like me ka rula, i ke ano o ka hopelessness a me ka lilo o ka hoihoi i loko o ke ola, e like me ka pono me lethargy, apathy a me ke kaumaha e hele ma 3-4 pule ma hope o ka hoʻomaka 'ana o systemic hooponopono.

Kekahi o ka mea nui keakea o kēia mau ai 'o ka antidepressant discontinuation maʻi pale, i hoike mai ai ia ia iho me ka pahi, a kipi hoopau wale o lākou ke komo.

Pehea e pili?

1. Inā 'oe i diagnosed naau maʻi, hakuʻala a ake maʻi eʻoiaʻiʻo, e hōʻike i kou kauka.

2. Antidepressants hana pākahi, no laila, ke hoʻomalu, e koho i ka lāʻau i mea e pono manaʻoi no oe.

3. Ma kekahi hihia, hoʻokahi ka lapaʻauʻia mea,ʻaʻole lawa ka, kou kauka i koi 'ia i ka wā hoʻokahi? Eaia o ka lau (tranquilizers a me antidepressants, antipsychotics a me kekahi anticonvulsant ai'). Ma muli o kaʻike, a me ka mālamaʻana i kou somatic ana, he hoʻomalu, e koho i ka ai 'i e e hiki ke hoʻokō kekahi i kekahi, a e ole i ka hopena maikaʻi' ole ma o ka kanaka kino.

4. E hiki ole ana e lawe antidepressant lapaʻauʻia koke, a me ke kūkā pū me ka hoʻomalu, e like me keia e worsen i ka holo ana o ke kaumaha, a i kekahiʻano o kaʻawaʻawa loa physiological naoh.

5. He nui ka poʻe e noi aku paha ia mea hiki ke inu antidepressants a me ka waiʻona pu. A pau ao ana i ka ai 'i hōʻike mai ia mea mea categorically unacceptable, no ka mea, hiki i' inoʻino loa i ka ua'emi'ōnaehana, a me ka make.

withdrawal ole addictive?

Ma ia hihia, ina e lawe antidepressants no ka lōʻihi manawa, a laila, no ka mea ke kumu, papani iho la i ho opa ao, hiki i discomfort, e like me emotionally lolelua ka hana, luhi, Muscle aches, pōniuniu. A pau kēia mau symptoms i ikeia like antidepressant discontinuation maʻi pale. I mea no ke aha kauka Paipai 'ke kiʻekiʻe o hoemi i ka mahele lāʻau o ka lapaʻauʻia loaa mai, a, e hana ai ma lalo o ka hooponopono ana o hoʻomalu. Wale 'Oihana ke kōkua höʻike aku discomfort, ua lalau aku la ia i ka mea e pono ai normotonics, a hoʻomākaukau i ka muli o nā mea kanu. Inā ka lāʻau ua lawe uncontrollably, a laila, i kona hookohu ia i ho opa ao 'ōlelo, ka ke kāpaeʻana o antidepressants ke alakai i ka hiamoe ka haunaele, mahuahua uunu nui, a me ka pilikia a me ka mea'ōnaehana mānowai koko nenoaiu. Eia kekahi, ke kēia symptoms i ana:

• manao makau;
• maʻi palū-e like symptoms;
• nausea, ka luaʻi;
• cramps a me kaʻeha ma ka gastrointestinal'āpana;
• lilo o ka ōhumu, a me ka vertigo;
• loaʻa kūpono;
• lala tremor.

kahi o ka hopena

Mai ka keia ka mea hiki ke manao e pili ana i ka ikaika, a he pilikia kēia mau ai ', aha mea antidepressants i nā laekahi' ai 'e hiki Makuakane me ka kaumaha. Naʻe, ma mua oe hoʻomaka lawe ia lakou, kukakuka pu me ka hoʻomalu - psychiatrist a psychoneurologist ka mea hiki ke pohihihi mai i palapala mai o ka maʻi o oe a me ka laau, e kōkua Makuakane me ia.