Pseudomonas aeruginosa: ka hana a me nā hi'ohi'ona

Pseudomonas aeruginosa a Pseudomonas aeruginosa - hoʻoneʻe Gram pili i opportunistic. Ma ka'ano, ua hā'awi like'ia ka'āina, ola i ka lepo a me ka wai, ma nā mea kanu, ma nā wahi manu o nā holoholona a me nā kānaka. 'O paha paha ka microorganic pūnaewele'oi aku o nā mea e hiki ke mālama'ia i nā kaha wai i lawe'ia mai nā kumu kūlohelohe.

He aha oia i kekahi mau mai 'ē aʻe opportunistic koʻohune, no ke aha la oukou i kaʻu mea noonoo ana o ka poe kumu a me nä känaka' epekema,ʻo Pseudomonas aeruginosa? Ho'oma'awa loa i nā hana hana pilikino i hana'ia e kēia microeneganis, he ko'iko'i ke ko'oko'o i nā lā'au'alopelo. Me ka ma'i mycobacterium a me kekahi mau ma'i o staphylococci, no laila ka huakini kūpono loa i ka chemotherapy i kēia lā. Akā, ma kēia papa inoa,'o ia ke alaka'i.

'O kēia ke kumu o kahi biofilm e hana ai i kahi palekana, a me kahi pale e hana ai liposaccharides o ka membrane waho. A aia kekahi mau'oko'a e kū'oko'a ana i nā mea a pau e'ike'ia nei e nā lā'au'alopero.

Eia na'e,'o Pseudomonas aeruginosa, kahi hana pa'akikī no ka mālama'ana i nā lā'au lapa'au, he pilikino ia i ka phenol (2% solution), 3% hydrogen peroxide a me chloramine (0.5% solution). Ma ke kaiapuni, i loko o ka wai a me kahi anuanu humuhumu,'a'ole hiki i ke kino ke ho'omau no ka manawa lō'ihi, akā, no ka ho'opuka hou'ana. E pono ai no kona ulu ua manaoia e e 37 ° C wela, akā, no hoi ma 42 ° C bacillus hiki no e ulu ana.

Pseudomonas aeruginosa: hō'ailona

'O ka hana o ka mea kino i ka ho'omohala'ana i nā hō'ailona o ka hōmai, he mea nui ia,'o nā pūkuniahi, nā lumi lumi, nā lima polu, nā mea'ele'a (nā wāwae, e like me ke'ano) e hō'ike i kahi pilikia e pili ana i ka ma'i. Local lesions pinepine ana ma ke kahua o nā'ā a me postoperative na nakaka, ʻoki a me ka palapū. Huli pinepine i kahi lā'au no otitis, pyoderma, dermatitis. 'O ka hopena o ka hō'eha a i'ole ke kūkō, hiki i kahi hua bacteri ke ho'opili i ka ma'i o nā maka, a me ka'āpana urinary (pinepine me ka hāmele).

No ka mea hoʻoʻino keʻano o ka hanaʻana, a hiki ke hoʻoiliʻia no ka Pseudomonas aeruginosa, ua komo pū nō endocarditis (lilo nui o ka naau kiwikā), pneumonia, lolo abscess, meningitis, nń maʻi pale, i ke ami. Ma ke'ano laulā,'o ka ma'i i loa'a i kēia ko'oko'o, ke alaka'i pinepine'ia i bactousmia - ka ma'i o ke kino holo'oko'a ma muli o ke komo'ana o ka mea ho'olaha i loko o ke koko.

'O kahi hi'ohi'ona o kēia huapalapa ka ho'oka'awale'ana i nā hope hope a me nā exotoxins, hemolysin, cytotoxins, hana ki'eki'e proteolytic, ke kahakaha o hyaluronidase, ka hiki ke hana synthesize i ka waiwai starch-like i ke'ano o ka mīkini, kahi e ho'onui ai i kāna mau mea pa'a, a me kekahi mau pua'a. 'O nā'eke i hana'ia e kēia microinganism e loa'a me nā hō'ailona ko'iko'i o ka make'ana, ka wela nui. 'O ke'ano o ka lahilahi o ka'ōpū o ka Pseudomonas aioio ka pa'akikī, ka lapalapa o ke kakahiaka, ka hana a me ke'ano o ka hanu. Hana'ia ka lethality ki'eki'e (a hiki i 50-60%) me ka maleingitis, a i ka manawa e ola ai ka mea ma'i, hiki ke nānā'ia nā hanana i koe i ke'ano o nā ma'i neurologic.

Pseudomonas aeruginosa: ka lā'au

'O ka mea mua, he mea pono e ho'oholo i loko o ka ho'okolohua i ka'ike o ka mea ma'i i nā lā'au lapa'au. Ho'oma'a'ia o ka Pseudomonas aeruginosa mau ke koi'ana i kekahi mau hua'ōlelo'eleu (ma lalo o'elua). I loko o nā ma'i ākea, nā hopena ola, inā'a'ole he manawa e kakali ai i nā hopena o nā mea kanu, e kauoha i nā lā'au'alopelo, kahi e ma'alahi ai ka pa'ū, ma nā kau palena ki'eki'e. Ho'omākaukau lākou i ka papa hana penicillin o ka lima a me ke ono hanauna (amdinocillin, pitracillin, azlocillin). 'O ka hana nui'o Carbenicillin. Apply and cephalosporins - cefzulodin, ceftazidime. Ho'ohui pinepine'ia lākou me nā aminoglycosides. 'O ka ho'ohana kūpono a me ka maika'i o ka ciprofloxacin. Ma hope o ka loa'a'ana o nā hopena o ka lūlū'ana, ua ho'ākāka'ia ke'ano ho'olālā.

Me ka lohi, ka lō'ihi, hiki i nā ma'i e ola ai, no ka mea,'o Pseudomonas aeruginosa ka mea nāna i mālama. I nā kumu he nui, ua lawa ke koho'ia'ana o kahi mau lā'au'ae. I kēia mau lā, ua ho'ohana nui'ia ka bacteriophage Pseudomonas aeruginosa no ka mālama. Eia na'e, pono e ho'omana'o'ia i loko o kēia hihia, he mea pono no ho'i e ho'oholo i ka'ike o ka mea ma'i i ka huahana ola.