Uluwehi O "Nise". Na Ke Kumu no ka hoʻohana

Medicamentsʻeleu waiwai a mea he nimesulide noho nui Anati-hoʻoʻino a me ka analgesic hopena. Maoli mea he pili-steroidal lāʻau "Nise". Ua Ua hoʻohana 'ia no ka hana rheumatoid arthritis, osteoarthritis, arthritis, myalgia, arthralgia, bursitis, tendinitis, algodismenorei e hooluolu aku au i postoperative a me posttraumatic eha, kahua nihoʻeha a me ka headache, kuni okoa Kin. Available i loko o ka palapala o ka papa me ke keʻokeʻo ano me ka yellowish malu, a me ka tuko pīlali (akaka, ka malamalama yellow ole yellow) no mawaho hana. Nā papa i puni, biconvex shape a me ka Kaulu. Total 100 mg 1 papa he Nimesulide lāʻau "Naiz". Instruction papa helu adjuvants: palaoa pia, microcrystalline kelulose, me hydrogen kalipuna posapahate, paʻakai pia glycolate, makanekiuma stearate, hoomaemaeia talc, colloidal anhydrous ka silica i. I 1 g. O ka 1% tuko pīlali he 10 mg o nimesulide. Tuko pīlali auxiliaries i: propylene glycol, N-meto-2-pyrrolidone, macrogol, carbomer 940, isopropanol, butylated hydroxyanisole, potasiuma posapahate, thimerosal, ka wai, flavoring.

No ka mea manawa mua o ka lāʻau i loaʻa ka nimesulide, Ua hoʻokuʻuʻia i loko o Italy (no ka laʻana, «Aulin» a «Mesulid») i ka makahiki 1985 a me ka mea a ianoiyuaa a loaʻa i loko o oi aku mamua o 50'āina: France, Portugal, Greece, Kuikilana, Pelekiuma, Mexico, a Brazil . Eia naʻe, ai 'me ka nimesulide i loko o ka United States mea i kuai lilo aku. Medicine "Nise" ke ao nei i ka like paha, ka mea i loaʻa ma lalo o ka kēia hoʻokuleana kope ' :

• «Sulide», «Mesulid», «Nimalox» (Brazil, Greece);
• «Aulin», «Mesulid» (Italy);
• «Coxtal» (China, Czech Repubalika, Pulakalia);
• «Sintalgin» (Brazil);
• «Eskaflam» (Brazil, Mexico);
• «Octaprin» (Pakistan);
• «Nise» (India, Rusia, Venezuela, Vietnam, Ukraine);
• «Nilsid» (ʻAigupita);
• «Ainex», «Drexel», «Edrigyl», «Enetra», «Donulide», «Heugan», «Mesulid», «NeRelid», «Nexen», «Minapon», «Nidolon», «Nilden» (Mexico) ;
• «Nimed», «Nimesil», «Nimutab», «Nimedex», «Nimdase», «Nimopen-MP» (India);
• «Nisulid», «Nodard», «Nicip», «Nimcap» (India);
• «Novolid», «Relmex» (Ecuador);
• «Remisid» (Ukraine);
• «Scaflam», «Sulidin», «Scaflan» (Tureke);
• «Modact'Ira lāua" (Pakistan).

Ka lāʻau i ka loa a me ka kokololio multifactorʻano papa hana o ka hana, a me ka mea he inhibitory ia ma luna o ka'ūhū Punk-2 (cyclooxygenase isoforms kekahi o hooponopono ana i ke kahua o prostaglandins mai arachidonicʻakika). No laila, ua hoʻohana 'ia ka lāʻau "Nise" i loko o ka iapaau ana o ka laulā huahelu o hoʻoʻino ana. Manual ia kekahi kona hoʻohana no ka iapaau ana o ka huʻiʻeha, ka symptomatic lapaau o osteoarthritis a iniiaiie dysmenorrhoea (cyclic pathological ana i loko o nā lā o ka menstruation, hoikeia mai loa abdominal ka eha,) ma ka adolescence a me ka adulthood. Nimesulide ua hoʻokāʻoi 'e malu ai no ka gastrointestinal'āpana hoʻohālikelike me nā NSAIDs.

Mau makaukau "Nise" Ua häʻawi mai me ka lōʻihi mālama nui. Alakaʻi, noka mea hoʻomanawanui iki mai me ka naau e hemahema, arterial hypertension, mimikō o type II. Akā, no ka mua kanaka mai e pono ai i ka? Iaea o dosing regimen. Lōʻihi-manawa hoʻohana ana i ka lāʻau 'koi kahua hoʻonohonohoʻana ka mālamaʻana o nā puʻupaʻa, a akepaʻa. Keʻano o ka adverse reactions (i loko o ka palapala o ka heartburn, nausea, ka luaʻi, diarrhea, gastralgia, ulceration o ka gastrointestinal mucosa, headaches, pōniuniu, loliʻana, allergic reactions me ili poʻe noʻonoʻoʻole, anaphylactic nń) o ka hōʻailona, e nīnau aku i ke kauka . I loko nō o ka mea i huahana i loaʻa ka nimesulide, he hailona, e puku i ka "Nise" i loko o kekahi o nā analogues me ke kauka o ka kuhikuhi ua ole paipai.

"Nise" mea pepehi lāʻau overdose. Alakaʻi wehewehe kona symptoms. O nā drowsiness, lethargy, nausea, ka luaʻi, gastrointestinal kahe ana ke koko, hypertension. Oe i ka mahina eha ma ka epigastric aina, naehana hanu kaumaha, huʻiʻaʻa puʻuwai e hemahema, anaphylactic reactions, a me ka coma. I Ina o ka overdose hiki ole e pili ana i kekahi antidote, no ka mea, ka mea wale hakuʻole, no laila, ke kauka prescribes he symptomatic Inc. Ma ka hora mua ma hope o ka hanana o kekahi o kēia mau symptoms holoi i ka hoʻomanawanui i'ōpū, a haawi ho'ā 'charcoal. Hemodialysis ma keia hihia mea i kona mana. A lohe o ka lawelawe ana i ka lāʻau 'koi akahele ina ka poʻe me ka nimesulide ia ai' e like me "Phenytoin", "Digoxin ', diuretics, ai' likiuma a me nā NSAIDs, antihypertensives, antidiabetics," cyclosporin "a me ka" MTX ". No ia mea, pakiko "Nise" ua ole ae.