ACAT a AlAt - ke kūmau no nā mākua a me nā keiki

AlAt (piha inoa - alanine) - he'ūhū hua mai i loko o ke ake, a lawe 'ana i loko o'aminoʻakika pūnao. Inā i ka uku o ke koko AlAt oi, e hiki keia i ka mua hōʻailona o ka maʻi. Ka'ūhū oia i ka nui nui ahu waiwai i loko o ke akepaa, skeletal Muscle, hakuʻala a me cardiac Muscle. A me ka emi ana o ka mea, i loko o ke koko lāʻau lapaʻau, ke koko no ka AlAt alii poe i negligible nui o ka waiwai. Nui loa ia e hiki i ka mua hoailona o kekahi pathology, akā,ʻaʻole e mau ana.

Inā ka halepaahao kino, a iloko ona i kakauia i ka waiwai no kekahi kumu hoʻomaka e wāwahi ai, a laila, i ke koko i loko o nui na mea e hiki mai AlAt. Kūmau i loko o ke koko lāʻau lapaʻau - ma kahi o 0,1 e 0,68 mmol / ml 30-40 hola a me huahelu no hano .. Ia mea, i loko o ke ola i ke kanaka kino i ka mea uuku loa na mea i hiki mai AlAt. Kūmau no ka wahine ka mea, mea i ka 31 iniha, no hano, no na kanaka - i 41 iniha, no hano. Mahuahua AlAt hiki i maʻi e like me hepatitis,ʻawahia ake poino, a me akepaa Ka maʻi 'aʻai, cirrhosis, alcoholism, naau maʻi - he myocardial infarction paha naau e hemahema, make o skeletal Muscle. Nō hoʻi, ma hope o ka nui kŰia a'ā ke mahuahua AlAt. Ke kūmau hoi pinepine ana e oi aku i ka wa a ka nunui naau hoouka. A ia mea mea ulu i loko o ka incubation au o ka hepatitis B maʻiʻaʻai.

ACAT (i kona piha inoa - lutamat oxaloacetate transaminase ole aspartate) -'ūhū lehulehu mea nui loa i loko o ka myocardium, ake, hakuʻala a me skeletal Muscle. Kēia'ūhū Ua oi hana i loko o nā kānaka ma mua o nā wāhine. Inā ACAT ha awina i loko o ke koko, e hoʻonui loa, ka mea, Mei hōʻike mai ai i poho i ke kino keena, ma ka liʻiliʻi loa - he 'aʻe' ana i ka mana o ka mea nana i haawi mai. Inā he ua, ua poino i ka naau Muscle, ma keia hihia he mea i ke kēia nui o ka ha awina o ka ACAT - kona mama no ke hoonui i ka 20 manawa. Ka hou foci o necrosis i loko o ka myocardium, i ka nui o ka maʻiʻo o ka'ūhū i loko o ke koko. Koko kūmau AlAt keiki mea nui haʻahaʻa ma awelika ma mua i loko o nā mākua. Ma ke koko o ke kaikamahine elemakule 7 i ka 12 makahiki, o ka uku o ka 13-21 hoʻopili like i kekahi, a me na keiki o ka hookahi makahiki, i kēia kaula, i ka lalo a me ka hoaka o ka hiki e oi aku ma ka awelika o ka 4 huahelu. Ma adolescents, i ka uku o ke koko AlAt i e haʻahaʻa ma mua ia o nā keiki ma lalo. No laila, i loko o kaikamahine elemakule 13 i ka 17 makahiki, no ka uku papa koa mai ka 10 a hiki i 13 iniha, no hano, ma keikikane o ka hookahi makahiki pūʻulu - mai ka 10 a hiki i 15. kēia mea he awelika huahelu no adolescents AlAt. Kona kūmau no ka mua kanaka 'aʻole e hoʻololi, a no ka mua wahine - ua hoʻemi e 2-3 huahelu no hano.

A me ka Alt, a me AST i nā'ūhū - aminotransferase. Mau nā'ūhū iʻeleu loa ma ke kino o kekahi kanaka. Ka hapa nui o ka Alt i loko o ke ake, a me ka ACAT - i loko o nā nā'aʻaʻa o na nāʻiʻo - ka oi aku i loko o myocardial'aʻaʻa o ka naau Muscle. ACAT ua haku o ka cytoplasmic a me ka mitochondrial isozyme isozyme. 80% o ka ha awina o ACAT e kau mai maluna o ka cytoplasmic isoenzyme. Ma ke koko lāʻau lapaʻau o kēia mau isozymes ua ana i ho'ākāka 'wale cytoplasmic.

Normal AST, Alt loa no kela lesions o ke akepaʻa. I ka pau, lesions o kanakaʻona mau, lāʻau lapaʻau aʻawahia, cirrhosis, hepatitis, a no laila, ma luna. Inā heʻawahia akeʻapu kōheoheoʻana ma muli o ka 'ai, inu ana i kekahi mau lapaʻauʻia, a laila, i ka ACAT kūmau AlAt loa. Kekahiʻawahia 'ole ma ke akepaʻa ke alakai ia ia i ka hopena. Norma AST, Alt, a ua mahuahua muli o nā kumumea i i mea e hana ai me ka pilikia ma ke akepaʻa. Mau kumumea nā i ka makahiki o ke keiki - i ai i eono mahina (mea ulu i loko o ka uku o kēia nā'ūhū i loko o nā keiki mea maʻamau), pōʻino i na nā'aʻaʻa o ka naau Muscle, wela hahau ana, papa o ka maʻi FOBS i loko o na keiki, Muscle li nui, hemophilia, obesity, a he nui na mea e ae.

Norma AST, Alt, a me ke kino mea haʻahaʻa. Kēia hana no ka hoʻokō 'ole' hakuʻala, pyridoxine deficiency, 'o ia hoʻi, wikamina B. Ua hoi e pono e i ka hopena o ka hai hemodialysis. Ua hiki e loa maʻamau i ka hapai understated (hoala) ACAT paha Alat. Kona kūmau i hāpai keiki ua pinepine aʻe ma muli o ia ka mea i ka nenoaiu o ka kūkuluʻana lawe wahi i loko o ka expectant makuwahine.