Antidepressant 'Azafen', nā kuhikuhi no ka ho'ohana'ana, nā hopena'ao'ao

Uluwehi O "Azafen" pili ia i ka pae ana o ka tricyclic antidepressants. He hana ho'okipa nui kona, ka pāpā kū'ē a me ka no'ono'o. Ho'omaopopo pinepine'ia kēia lā'au lapa'au no ka mālama'ana i ke kaumaha a me ke kūlana ha'aha'a, e like me:

- endogenous;

- hō'ailona;

- exogenous;

- ka wai'ona;

- makemake;

- e'ōlelo i nā manawa pōuliuli o ke'ano ma'amau.

'O ka mea ikaika o ka lā'au lā'au "Azafen" hō'ike'ia ka inoa'o pipofezin. 'O ke'ano o ka hana o ka waiwai ke kau'ia ma ka hana'ana i ka hopu'ana i nā neuronal o nā norepinephrine a me ke serotonin. 'O kēia ka hopena i ka pi'i'ana o ka pipophezin ma ka pūpū o ke kikowaena a me ka pau'ana o nā hō'ailona o ka hina.

Aia kekahi'oihana ma luna o nā lā'au like'ole o ka hana antidepressant o ka lā'au lapa'au "Azafen",'o ke a'o'ana no ka ho'ohana'ana i ka inoa no ka nele o kāna mau ma'i ma'i. Ua Ua kaulana like me ka maikaʻi keiki o ia hoʻi, "Azafen" ma affective kāna hana, hoʻonāwaliwali i ka somatic, psychic a me ka autonomic kāna hana pili i kaumaha. 'O ka maika'i o ka lā'au lapa'au'o "Azafen" mau kuhikuhi no ka ho'ohana'ana e ho'oholo i ka asthenia e hana'ia ma muli o nā pilikia nui o ke kanaka. Iloko o ka hooponopono ana o ka lāʻau i loko o nā mea maʻi nalo ka iini, stress. Aia kekahi mau hana maika'i i nā po'e ma'i me ka anorexia neurogenic, ka mea ma'amau a moe ka moe i ka lā.

'O ke kauka "Azafen", e pili ana i kāna waiwai pharmacokinetic, he pai ka digestibility, ua mālama maika'i'ia ma waena o ka'ehā o ka lā'au o ka'ohe, kahi nui o ka bioavailability (80%),'o ka nui o ke kaulike ma ke koko e hiki i loko o 2 mau hola. I loko o ke ake, e hana'ia ka biotransformation o ka pipofepine i nā mīkini metabolites e pono'ole, e ho'onui'ia e nā pu'upa'a. Ho'opau'ia ke kino mai ka lā'au lapa'au ma hope o 16 mau hola.

Iapaau ana o ke kaumaha o ka likeʻole kêia kanaka mea he kumu PAaIEN no ka hoʻohanaʻana i ka lāʻau "Azafen" manual hoʻomōakaaka ka moku'āina, helu a pau ano depressioy, paku ole ia i ai '.

Loa'a nā hō'ai'ē no ka ho'ohana'ana i ka antidepressant "Azafen",'o ke a'o'ana no ka ho'ohana'ana e hō'ike i nā kūlana i kū'ole kēia me ka lā'au:

- ma'i diabetes;

- kaʻana like me Mao nā mea kūpale ;

- ka hō'oki āpau, ka kīnā o ka na'au, IHD;

- kahepa hepīpī ai'ole'ole paha;

- nā ma'i'eha o kekahi kūlana ki'eki'e;

- kahi kūlana ma hope o ka hō'eha nui'ana o ka hele'ana o ka ma'i (ma hope o ka hahau'ana);

'O ka hānau'ana, ka lactation.

Pono e maka'ala i ka hopena o nā hopena i ka manawa o ka lawelawe'ana i ka lā'au lapa'au, ua hō'ike'ia e nā nūnū a me ka ma'i kīkī, nā hopena o ka ma'i, ka lua'i a me ka nausea. 'O ka mea pō'ino,'a'ohe'ike e pili ana i ka mālama'ana i ka loiloi lā'au, ma ia mau'ano, he hō'ailona. I ka nīnau o ka hō'ai'ē, pono mākou e ho'ohui i ka pilikia o "Azafen" a me ka wai'ona. 'O kēia'elua mau mana'o kū'oko'a'ole, i ka wā e mālama ai, he pono e'ae i ka inu'ana i ka wai'ona a me ka ho'ohana pū'ana i nā lā'au'alo'olo e loa'a ana i ka ethanol.

'O ka "Azafen"'a'ohe ona'ano cholinolytic, no laila,'a'ole e hō'ole kekahi i ka lā'au lapa'au no nā mea ma'i me ka glaucoma. Ma waho a'e o ka laulā'ole me ka wai'ona, hiki i ka hopena o ka ho'ohana'ana i kēia lā'au lapa'au me nā antioagulants, antihistamines a me nā lā'au lapa'au a pau e ho'onāukiuki ai i ka pūnaewele pūpū. Pono e ho'omaopopo'ia ka ho'ohui like'ana o "Azafen" me nā lā'au antiepileptic e ho'emi ana i ka pono o kēia hope.

"Ho'oku'u maika'i'ia'o" Azafen "e like me ka'ōlelo i kākau'ia, he 5 makahiki ka lō'ihi o ka noho'ana, pono e mālama'ia i ka 25 mau.