APTT hoala: no ke aha la e keia ahaʻia? E hoomahuahua oe i APTT i hāpai keiki

APTT (ho'ā 'hapa thromboplastin manawa) - keia mea he mea nui anakahi o ke koko clotting, e leie aku oe i ka hoʻoholo' ana i ka pilikia o ke koko clots a me ka hanana o ke kahe ana ke koko. Pono ke kālailaiʻana i ka hana o ka coagulation'ōnaehana, e hiki ke hoʻoholo pehea hanahana loa ka maʻi mea, a koho i ka hana pono. E ka kamailio e pili ana ia.

Pehea o ka APTT hōʻike?

Kālailai i ka uku o ke koko clotting kōkua e hōʻike systemic abnormalities i IeAUPIIe, IAa IO hōʻike 'ana i loaʻa nā' aʻe 'ana o laupaʻi, a qualitative nā hoailona o ke koko.

Oia i Ka Ikepili ua lawe mai i loko o ka maopopo kumu. Mua, o ka mea e e hookolokolo aku la ia, e pākuʻi i ka Tube i loaʻa i ka anticoagulant ka paa o ke kalipuna Ion, ma muli o ia i ke koko i ole clot. Hoʻokōʻia centrifugation, e hookaawale i ka wai koko, mai na platelets a me nā kumu mua. Mahope, i ka hoao ana şarkı i huiia phospholipids, kalipuna koloriside a me ka activator. Hoomaka ana e Loiloi i ka manawa i loko o i ke koko clot ua hana.

Phospholipids haʻalele i ka extrinsic alahele o coagulation, a me ka kalipuna koloriside mea nui ka waiwai i loko o ke kaʻina hana o ka coagulation. Oia i Ka Ikepili 'aʻole i hiki maopopo loiloi i ke kaʻina hana o ka thrombus ho okumu, akā, e kokua, e kuhikuhi abnormalities i loko o ke ana, a hiki i laila, nana no na kumu o keia kŰia.

I kekahi manawa e huli mai ia APTT māhuahua ai ua hoʻemi. Ua kuhikuhi mai la lakou i ka na pilikia ma ke kino.

kūmau

Ke anakahi Ua ana i loko o kekona, a hiki ĸokoĸa ana nä pane ma muli o ka mana, makahiki o ka hoʻomanawanui, a me ka hana. APTT Normal makua kanaka mea mai ka 28 a hiki i 40 kekona. Ma nā pēpē i, keia aka mea kiekie ae no 1-3 kekona.

Ke kiekie koko aPTT ua diagnosed wā kekahi clotting ololi ua hoemi paha, a mahuahua nui e oi aku mamua o 30%. Hoemi uku pinepine Hōʻike hypercoagulability.

Hoʻoholo 'ana o APTT i loko o nā mākua a me nā keiki ua paa e hooholo i ke kumu o ka ilihune koko clots, e like me ka loiloi i ka laulā o ka iapaau ana me anticoagulants.

Kumu no ka hoʻoulu APTT

He nui loa kōkua ka wā e loaʻa mai i APTT māhuahua. He aha aʻole ia ke ano o? Kēia ka hana i ka wā ma laila mea i ka pilikia o ke kahe ana ke koko. Ke kumu paha e:

1. Lawa ka nui o ka wikamina K i loko o ke kino. Ua kuhikuhi mai la lakou i ka pilikia ma ka digestive'ōnaehana, no ka mea, i kēia wikamina ka paipai 'ana i ka hoʻololi kemikala o intestinal koʻohune. Ua kekahi mea nui no ka maʻamau functioning o nā mea a pau clotting kumumea. Kona deficiency ia lŘlŘ ma muli o ka dysbiosis, me heʻano pākīkēʻai, kūpono ma ka lōʻihi-māpuna lapaau me antibiotics.
2. Aaiaoe abnormalities mea i pili i ka 'aʻe' ana o ka qualitative, a laupaʻi kiko'î o ke koko. Ma keia hihia, 'inideka APTT mahuahua nui ae.
3. Postpartum hemorrhage, huʻi leukemia, DIC.
4. Hemophiliaʻano A, B, C.
5. Ke alo o nā mea'aʻaʻa i loko o ke koko ma luna o ke pelu kumumea a me lupus anticoagulant.
6. Kūpono makaukau no Ka Ikepili, ka accidental ingress o heparin i loko o ka hāpana.

Hoomahuahua ae la lakou APTT, he keiki e hoi e ku pono ana i kēia mau kumu.

APTT i hāpai keiki

Ma hāpai keiki, o ka ho'ā 'hapa thromboplastin manawa ua hoomaka ana i ka hoʻololi' ana i. Inā i ka uku no ka awelika kanaka mea ma waena o 28 a hiki i 40 kekona, ma ka hapai wahine ia mea 17-20 kekona. Kēia 'o ia hoʻi i ka mea, ua hoemiia. Oia loli hoʻonāukiuki i nā kēia kumumea:

• Ma keia paakiki wā i loko o ka wahine o ka kino, he hou utero-placental holo. Placenta ninoieo o ka ai iiiaanoaa o na moku. E like ina mea i waiho i kekahi meaʻuʻuku poe, i ke koko poho hiki e nui. IeAUPIIe, IAa IO poe ia lŘlŘ aie i ka māhuahua uterine leo.
• I hanau i ka wahine ana i haalele mai i 400 ml o ke koko. Kēia ka hana nui koke, a me ka coagulation nenoaia e e makaukau keia mau mea he nui kahe o ke koko, pela hoi clots e hoomaka ana i ka e hana koke i ka pale hou ke koko me keia poho.

No ke aha la APTT ke kiekie ma ka hāpai keiki?

APTT ua hoomahuahua ia ina ka clotting manawa ua oi aku mamua o 40 kekona. Kēia ho'ēmi i kā ka hiki ana o ke koko clots e hana, kūpono ai i loko o ka pilikia o ke kiʻekiʻe koko me keia poho.

Maʻamau APTT māhuahua ina he wahine hapai ua lawe antibiotics, heparin, aspirin a me thrombolytic ai '. Mua ia e ikea ai, ka mea e hai aku i kā lākou mau kauka.

Ke mahuahua ma APTT Hōʻike he emi i loko o ke koko o ka hiki e clot, a ia ia lŘlŘ i loko o ka hahai pathological keia:

• Ake maʻi e lei ana i olelo ia hepatic ka hoʻokō 'ole, a me a me ka cirrhosis. Ma keia hihia, he mea ka 'aʻe' ana o hoʻololi kemikala o clotting aʻe i loko o ke koko.
• Ka nele o ka wikamina ke K, ia lŘlŘ ku ei ke kāʻei kua o ka dysbiosis i loko o ka gut, e like me ka manawa i kūponoʻai.
• Leukemia.
• Hemophiliaʻano A, B, C. kēia mea he hereditary maʻi wehewehe aku ma kekahi congenital deficiency o clotting aʻe, pinepine kūpono ai i loko o kekahi noho'na makaainana i ulu kahe ana ke koko ana.
• Av Willebrand ka maʻi.

ka hopena

Ka Ikepili ma ka APTT pono lawe mai ma mua o ka forthcoming hana e loaʻa mai ana a paa i ke koko hiki clot. An mahuahua a emi mai ke kūmau Hōʻike i ka likeʻole pathologies. E pale i ka pilikia o ke kahe ana ke koko, pono pela.