Ai ' "Metodzhekt" a me ka "Methotrexate" - He aha ka ke unuhi?

Ma kēia 'atikala i ka hoomakaukau "Metodzhekt" a me ka "Methotrexate" mākou noonoo. He aha ka i ka likeʻole ma waena o lākou? Ma keia hope.

"Metodzhekt" mea he anticancer konohiki, a mea he hiohiona immunosuppressive hookoia no, ia mea he folicʻakika hoa. Hiki ana i ka ke kelepona hele mitosis. Kona papa kuhikuhiE kuleana pili i kekahi hana i inhibition o dihydrofolate reductase, he ki'ūhū o ka hoemi dihydrofolate tetrahydrofolicʻakika. Ke kumu o ka lāʻau - mai ka 700 a hiki i 1100 rubles.

Ka loa kaulana mea like "Metodzhekt" hoomalolo o ka'Aukekulia "Methotrexate Ebewe".

kona kāki He ma ka laulā o ka mai 400 a hiki i 1200 rubles.

Haku mele 'ana "Metodzhekta"

I ka papa kuhikuhiEʻeleu 'Oponopono o ka lāʻau mea methotrexate disodium. Additional eiiiiiaiou: paʻakai koloriside, paʻakai hydroxide, i puhi ia i ka wai.

He mana me ka pili ana i ka? Aneii a me ka hikiwawe loa ulu keena. No ka mea pili i ka epithelial keena, a malignant neoplasms.

I mau palapala noi accumulates i loko o nā'aʻaʻa. Excreted ma nā puʻupaʻa a me ka bile. Inā 'oe compromised hakuʻala hana, excretion mai i ke kino' aʻole hoʻi ia. Ua hiki no hoi 'ūlōlohi mai ana a me ka poe ilihune ake kuleana pili i.

I ka haku mele 'ana o "Methotrexate Ebewe"

E like me kekahi hapa o ka lāʻau o ka mea hana 'Oponopono - methotrexate. Ua loaʻa immunosuppressive, Anati-ʻeho waiwai.

He mea maikai bioavailability excreted ma ka mimi a me dala uuku o ka bile. Ua mālama i loaa i loko o nā'aʻaʻa i loko o ka palapala o metabolites.

No laila, "Metodzhekt" a me ka "Methotrexate" - He aha ka ke unuhi? E like me ka mea haku mele a me ka hana i kokoke'ālike.

Ma kekahi mau hihia, o ka ia "Metodzhekt"?

Uluwehi O "Metodzhekt 'ma ka oncology ua kākaʻikahi i hoʻohana. Ua Ua hōʻike no ka ili maʻi a me nā maʻi o na ami, e like me:

• Psoriasis, i mea pilikia i ka pono.
• Rheumatoid arthritis.
• Nā 'ōpio arthritis.
• Psoriatic arthritis.

Triggered immunosuppressive a Anati-hoʻoʻino waiwai o ka lapaʻauʻia. Kēia wehewehe i ka laulā i loko o kēia mau maʻi puʻuwai.

Ka hoʻohana o "Methotrexate" lāʻau

Holo nōhie, "Methotrexate" i hōʻike mai no ka iapaau ana o ka maʻi 'aʻai.

• huʻi lymphocytic leukemia;
• trophoblastic maʻi;
• ili Ka maʻi 'aʻai;
• cervical Ka maʻi 'aʻai, a vulva;
• Ka maʻi 'aʻai o ka esophagus;
• squamous aeea carcinoma o ke poo a me ka ai;
• Ka maʻi 'aʻai o kaʻaʻa puʻuwai pelvis a me ka ureter;
• a osteogenic sarcomas myagkokletochnoy;
• Ewing ka sarcoma, akemāmā Ka maʻi 'aʻai, umauma Ka maʻi' aʻai;
• germ aeea hikoko o ka testis a me ka ovary;
• ake Ka maʻi 'aʻai, hakuʻala Ka maʻi' aʻai;
• retinoblastoma, medulloblastoma;
• penile Ka maʻi 'aʻai;
• Hodgkin ka maʻi.

A eia hoi, ka mea e e hoʻomaopopo i ka medicament ua noi ia, a me ka loa ano o ka psoriasis like loa me ka ina o ka loa rheumatoid arthritis (inā kūpono Inc ua ineffective).

Ia ka leo o ka mea like. "Metodzhekt" a me ka "Methotrexate" e hoʻohana no kekahi mau maʻi. Penei, "Metodzhekt" - no ka lapaau ana o psoriasis a me ka arthritis, like "MTX" - ma ka oncology. Akā, ka mea hiki ke hana, a laila, a me ka oi.

issuance

"Metodzhekt" - he melemele maopopo pāʻoihana. Kuai lilo aku la lakou me ka ohe, a i manao ia e lawelawe ma lalo o kaʻili, i loko o ka Muscle a me aa koko.

"Methotrexate" mea i loko o ampoules a me ka papa.

Like hoʻohana 'ia ai'?

Ke laʻau heluna o ka lāʻau i koho ma ka hele ana i kahuna lapaau e pono ma luna o kekahi kanaka manawa. O ka holo ana, ina he mea ole contraindications. Ua Ua hoʻohana 'ia i oi aku mamua o hookahi o ka hebedoma.

Ke hoomanawanui Pono e lawe i ka hoao mua ana. Ma mua, ma ka ana o ka hebedoma, e ka mea oioi hoao me dala uuku o ka lāʻau, ina ke kino reacts maʻamau, ka iapaau ana hiki ke lawe mai.

hoomalolo mea i pili I kaʻaoʻao 'ole. Mua, i ka palena iki mahele lāʻau o ka medicament ua wahahee, i mea 7,5 mg. A laila ia i nā māhuahua, me ka maikai tolerability, a na nāʻikepili.

Ma hope o kekahi mau mahina ma hope o ka noi mua oe e hai i ka hopena. Ka papa ke mau no ka lōʻihi manawa, mai i kekahi mau makahiki.

Ke hoʻohana i ka hapai keiki, a lactating wahine

Eia ka unuhi? "Metodzhekt" a me ka "Methotrexate" E ole e lawe i hāpai keiki, a lactation.

"Metodzhekt" meaʻawahia i ka fetus e alakai i nui ka haunaele ma ke ana, a hiki i kona make ana. Ma ka umauma waiu mālama i loaa, a hiki no hoi he kūlana maikaʻiʻole i ka pēpē ka ola.

Inā ka hāpai keiki i lapaʻau, ma laila e e undesirable hopena no ke keiki. No ia mea, Pono ka manao contraception i Inc.

Kakou e hoakaka aku i ka "Metodzhekt" ai 'a me "Methotrexate Ebewe". He aha ka ke koena unuhi, ka mea, ua maopopo. E hoʻokolokolo hou.

"Metodzhekta" Contraindications

Ke lapaau E ole e hoʻohana 'ina he mea kekahi hypersensitivity i na eiiiiiaiou. Aole hoi e ka mea e hoʻohana 'ia:

• Alcohol hainā.
• Ake a me nā puʻupaʻaʻelua.
• Hemodyscrasia.
• Imua o ulcers i loko o ka digestive'āpana, a me ka moʻolelo o ka lua.
• Vaccination (ma muli o ka ka ho'ēmiʻana o ka'ōnaehana paleʻea pane, e halihaliia oia iwaho vaccination eono wale mahina ma hope nōʻoe,? Eaia).
• Huʻi a me ka maʻi nā mea palahēhē (a me nā illnesses).
• Autoimmune maʻi.

Manao noi e ia inā he mea:

• Herpes.
• Pleural a peritoneal effusions.
• Ascites.
• Gout.
• Obstructive maʻi o ka digestive nenoaiu.
• Dehydration (pilikia ka wai kaulike 'o ia hoʻi, piʻi pū kaʻawahia).
• Asthenia.
• A nui lehulehu o ka bilirubin.
• Ka luaʻi, a diarrhea.
• E mālama nei Nine Inch a me ka pāhawewe Inc mōʻaukala.

"Metodzhekt" ho'āʻo ole, e koho i ka kūpuna, no ka mea, i ua o Nyos i ke akepaʻa a me nā puʻupaʻa. Ma kekahi, mai i hoʻohana "Metodzhekt" a me ka "MTX" ma UC (ulcerative colitis).

Ma kekahi mau hihia, ka mea, ua papaia e hoʻohana i ka lapaʻauʻia, "Methotrexate"?

I ka wa i olelo ia kanaka ake a / a me nā konāhua maʻi, leukopenia, thrombocytopenia, hāpai keiki, a lactation. i Immunodeficiency Hawaii i contraindicated no ka hoʻohana "methotrexate".

I ka lapaau hana rheumatoid arthritis a psoriasis, hookahi manawa i ka mahina, e haawi aku i ke koko biochemistry, e like me ma ka keʻena hoʻokolohua ana ia mea e pono ai i ka huli i nā puʻupaʻa, a akepaʻa, me ka alapine (frequency) o 1-2 manawa no elua mahina.

I ka psoriasis ua hana, ka Inc ua hoomau ma ka kūloko noi o ka lāʻau.

Inā e hiki mai i ka overdose, i ka hoʻomanawanui pono komo i ka folio o kalipuna iloko o ka eha hola mua.

AaOIeIOUIeXAOAaIN me nā ai ' "methotrexate"

"Methotrexate" papaia, e hoʻohana i ke kēia lapaʻauʻia:

- 'ole-steroidal Anati-hoʻoʻino ai';

- penicillin antibiotics;

- sulfonamides;

- valproicʻakika;

- colestyramine;

- mercaptopurine;

- neomycin;

- paramomitsinom;

- omeprazole;

- retinoids;

- tetracycline;

- cyclosporine.

Mau mea na contraindications "Metodzhekt" o ka laau a me ka "Methotrexate". He aha ka ke unuhi? Reviews paipai i ka mea, e hoolilo like paakiki.

AaOIeIOUIeXAOAaIN "Metodzhekta" a me kekahi 'ano

I ka wā hoʻokahi? Eaia "Metodzhekta" a me ka 'ē aʻe ai' hiki aku ai kekahi i mahuahua kaʻawahia, a no ka emi i ka pākōlea hopena. Inā 'oe makemake e hui pu iho la i kekahi mea, e mea maikaʻi, e hai aku i ka hoʻomalu.

"Metodzhekt" ia me ka mālama nui me:

• Hepatotoxic ai '.
• Ai ', hana kaumaha koko.
• Ai 'e aloha ia i ka iwi lolo.
• Kanakaʻona mau nā mea inu.
• Antibiotics.
• NSAIDs a me salicylates.

Pāpā papa inoa o ka laau mea nui nui iho la ia. Ua pono e hoomanao i ka AaOIeIOUIeXAOAaIN me ka "Metodzhektom" e i loa kaumahaʻawahia kaʻapu kōheoheo o ke kino (make ua i hoʻokoe '). I kekahi manawa e hiki ke alakai i ka ili maʻi 'aʻai.

Green kī a me ka kope e banned no hoi, e like me ka pono i inu mai ka purine alkaloids, theophylline a me ka caffeine. Ke kumu no ka mea - ino hoʻokaulike me ka methotrexate. Ua hiki me ka nui loa hookaulua lākou pōpilikia.

It E ke kaulana i ka wā e loaa ana Inc hōʻike wikamina pono a me ka hoomakaukau ana i loaʻa ka folate, no ka mea, ka mea, emi ka meaʻawahia waiwai.

A lāʻau e koho - "Metodzhekt" a me ka "Methotrexate"? I ka maikaʻi? Ma keia hope.

ʻaoʻao waiwai

ʻaoʻao 'ole paha e kekahi, akā, loa pinepine e loli ai i nā loko o ka gastrointestinal'āpana. Me ke alapine (frequency) a me ka oolea ka mea, e ala mai, ke kaumaha ma muli o ka mahele lāʻau, a me ka kanaka ano o ka meaola.

Ikeiaʻaoʻao waiwai iʻano nui:

• Stomatitis.
• Nausea.
• Kaumaha.
• Anemia.
• Dermatitis.
• Headache a me ka pōniuniu.
• Excessive sweating a me ka mai kuni.
• Allergies a anaphylactic kŰia.
• Pericarditis.
• Thromboembolism.
• Interstitial pneumonia.
• Ke Kula Kaiapuni 'infectious maʻi.

kekahi manawa:

• Ka luaʻi.
• Alopecia.
• Vasculitis.
• Pharyngitis.
• Paresthesia o ka lalo lala, manamana lima a me nā manamana wāwae.

Loa pohihihi keia:

• Convulsions a me ka lōlō.
• Ke kākoʻo hoʻopilikia.
• Pulmonary insufficiency.
• Myalgia.
• Osteoporosis.

E ulu pancreatitis, mimikō, impotence, infertility, a hiki loa i ka muli o hikoko.

He aha ka i ka likeʻole ma waena o na ai '' Metodzhekt "a me ka" Methotrexate "? Kēia ninau mea o ka hoihoi ana i na mea he nui.

E hōʻoia i ka i regular examinations i ka poe e hoomanawanui i ka poe e ke "Metodzhektom"ʻia. Pela ka mea hiki ke hooki intoxication. Loa ka hopena o keia weliweli, o hiki mai ona.

Pāpā holoʻana i Inc a me ka hana me ka weliweli hana.

Next, noonoo i kaʻaoʻao hopena o ai 'e like me "Metodzhekt" a me ka "MTX". He aha ka i ka likeʻole ma waena o lākou?

ʻaoʻao 'ole "methotrexate"

Ma ka hapa o ka digestive'ōnaehana i e hoikeana o ulcerative stomatitis, anorexia, gingivitis, pharyngitis, nausea; ma pohihihi keia hoopii - diarrhea, melena, enteritis, pancreatitis, hepatic necrosis, cirrhosis, momona atrophy, periportal fibrosis.

hematopoietic'ōnaehana hiki pane leukopenia, anaemia, thrombocytopenia.

Central ko mākou hopohopo'ōnaehana - luhi, pōniuniu; ma pohihihi keia hoopii - headache, aphasia, sleepiness, convulsions.

Reproductive'ōnaehana - he 'aʻe' ana o oogenesis a me ka spermatogenesis, oligospermia, menstrual paewaewa, ua hoʻemi libido, impotence.

Urinary nenoaiu - hematuria, cystitis, loa hoʻopōʻinoʻaʻa puʻuwai kuleana pili i.

Ke hoike mai i ka i kēia allergic reactions: wela, hoemiia e kū'ē'ē mai i ka maʻiʻaʻai; ma pohihihi keia hoopii - urticaria,ʻawahia epidermal necrolysis, Stevens-Johnson maʻi pale.

Dermatological reactions - ili poʻe noʻonoʻoʻole, photosensitivity, pigmentation kāna hana, huehue, maʻi hēhē.

I ka wā i kekahi adverse reactions i ka lāʻau e koke leka uila i ke kauka.

overdose

An overdose ka pilikia a hiki i ka hematopoietic nenoaiu. Ma kēia hihia, na meaola mea he hydration. Kēia hiki oia i ka excretion o kaʻeleu waiwai. I häʻawi mai ai iä loaa folicʻakika.

Nā kūlana a me nā hua'ōlelo

E noonoo "Metodzhekt" a me ka "Methotrexate". Ke koena unuhi ma ka holopapa ola ana o kekahi i loaʻa.

Ka maloo, pouli wahi ma ka wela, aole e oi aku 25 degere, e malama mau lāʻau. E hōʻoia i ka hoʻomaʻemaʻeʻana aku, mai na keiki. Map a me ona mau mea, i contraindicated. Pa ahau ia ole i ke Akua.

"Metodzhekt" ukele no 2 makahiki, mai ka lā o ka hana, "Methotrexate" - 3 makahiki.

Mauʻokoʻa "Metodzhekt" a me ka "Methotrexate". He aha ka ke koena unuhi nae?

I e like me ka "Metodzhektom", e hiki ke koho i kekahi o ka kiʻiona ka pono o ka "methotrexate". eʻaoʻao 'ole hiki, akā, ma ka manao ana o nā mea maʻi, i hoʻomaka ai emi pinepine ia. "Methotrexate" mea i loaʻa i loko o na papa, no ka mea, he nui loa nā mea maʻi, i kēia palapala Ua oi pono.

No laila, ua hōʻike mākou i loko o au mamuli o ka hana o ka "Metodzhekt" ai 'a me "Methotrexate". He aha ka ke koena unuhi, ia mea manawa kālaʻe.