"Mirapex": aʻo no ka hoʻohana 'ana, hōʻikeʻano, hōʻike manaʻo

Ma kēia 'atikala oe e aʻo a pau e pili ana i ka hoomakaukau "mirapex": pehea e puku i keia k, i mea kona kanawai, contraindications,ʻaoʻao waiwai, kekahi olelo ao me kona lima. Mau huaale hiki i'āno'ē hana a me ka hopena ma luna o ka hoʻomanawanui ka pane. No laila, ma mua ka lawe i kēia ka lapaʻauʻia "mirapex" kauoha no ka hoʻohana E e akahele? Anoee. E hai mai no hoi oe e pili ana i ka hoʻokaulike o kēia mau huaale a me nā ai '.

Hooloihiia "mirapex": mau 'ike e pili ana i ka lāʻau a me nāʻikepili no ka hoʻohana

Kaʻeleu waiwai o ka la hoomalolo "mirapex" ka pramipexole. Kākoʻo eiiiiiaiou papa: povidone, mannitol, pia, aerosil, makanekiuma stearate.

Me keia k Inc ua lawe idiopathic (kuokoa o nā lesions) maʻi pale o "restless wāwae" a me Parkinson ka maʻi e like me nā maemae Hawaii a me ka extrapyramidal kāna hana.

Product: huaale "mirapex PD" 3 mg, 4.5 mg, 1.5 mg, 0,75 mg, 0,375 mg. Ka mea i piha i ka blisters o 10 apana, a laila, ma ka pepa pahu.

keʻokeʻo Akala. Ka mea, i ka beveled palena a me i lalo shape ma na aoao elua, kekahi o i i ka walaau ole kamepiula.

Papa e e ia hōʻike waha, nānā 'ole o ka meaʻai. ʻai lāʻau ua 'ae i kekahi manawa. Ma keia hihia, ka mea e e holoi ia me ka wai. Paipai kela la i keia mahele lāʻau ua maheleia i ekolu kahua o ka hoʻonaʻauao.

Keʻano papa hana o ka 'ana (pharmacodynamics) "mirapex" papa

Haʻi'ōlelo pramipexole waiwai i maupaʻa ka hoomakaukau "mirapex" ua hōʻike hewa, a me ka kiʻekiʻe selectivity hoʻokāʻoi aʻe ana i ka pane o ka subgroup o dopamine receptors D2. Mahalo iā ia, compensated no ka nele o physical haʻawina i loko o ka hihia o Parkinson ka maʻi. He mea pono i ka ho'ā hope o ka dopamine receptors i loko o ka striatum. Pela pramipexole ua ālai 'ka degeneration o neurons e ia lŘlŘ aie i ka neurotoxicity paha ischemia. Ua inhibits 'ole ho'ēmi i kā ka uku o ka hoʻololi kemikala, pūnao, a hoʻokuʻu dopamine. Mahalo i ka pramipexole neurons i palekana mai kaʻawahia hopena o Anati-Parkinson konohiki "Levodopa". Kekahi manawa i kona kanawai emi prolactin (mahele lāʻau-e kaukaʻi).

Ma ka hihia o ke hooloihi ae i pono o huaale "mirapex" no ka iapaau ana o Parkinson ka maʻi (oi aku mamua o ekolu makahiki) a me ka maʻi pale o "restless wāwae" (oi ma mua o ka makahiki) i i hōʻike hoemiia ka hoʻokōʻana o ka pramipexole.

Biochemical keʻano o ka hanaʻana pili i ko lakou hoomakaukau ana "mirapex 'i loko o ka hoomanawanui ka kino (pharmacokinetics)

ʻeleu waiwai "mirapex" ka lāʻau ua pau loa ia, a hoʻomaka koke hoʻokemuʻia ma hope o ku una hooponopono. Kona nona iho no ka kaʻaluna (bioavailability) Ua kokoke loa - oi ma mua o 90%. ʻO kā mākou lehulehu o ka lāʻau i ka wai koko malama ma hope o 1-3 hola ma hope o kaʻaiʻana. Maʻai pramipexole omo kōmi emi. Ma keia hihia, no ka nui o ka digestible ai ua ole hoʻololi.

C nā polokina e hoopaa ana pramipexole iki (emi o 20%). He mea he nui hoi o ka makana ka leo - 400 nā lika, a 'o ia hoʻi e ka lehulehu i loko o ke koko mea haʻahaʻa. I ka mea uuku loa olohelohe ia lakou i ka lāʻau pūnao kaʻina. Kahi o 90% o ka mahele lāʻau "mirapex" pellets excreted ma nā puʻupaʻa, a me 80% - ua hoʻololiʻia. Nā feces pramipexole ua loaʻa i loko o ka nui o ka emi o 2% o ka hoopau dala o ka lāʻau. nei i hoomaemaeiaʻi'aʻaʻa a me ke kino fluids mai "mirapex" papa i ka mńmń holo 'awelika o ka 500 ml / min.

E ho ohana i "mirapex" lāʻau i hāpai keiki

Hiki au ke hoʻohana i hāpai keiki "mirapex" papa? Na Ke Kumu no ka hoʻohana ana i ka lāʻauʻo ia ka mea akaka i ka hopena o ka lāʻau ma luna o ka ulu ana o ka fetus i loko o ka opu a me ka lactation i ole, ua hoʻokolokolo.

Ke hiki hopena o ka pramipexole ma nenoai, a me nā luna kuleana no ka fertilization kaʻina hana i aʻo i loko o ia mea ma luna o na holoholona. Ia, aole ia i hoike aʻe 'o fetal? Acaeoey i hāpai keiki i loko o' Olu a me nāʻiole.

Excretion o pramipexole i loko o ka umauma waiu i ole, ua? Anoee. Kekahi hiki wale kuhi ana o ka waiwai hiki inhibit lactation, mai inhibits? Iecaianoaaiiie luteotrophic hōmona. Nolaila, mai lawe "mirapex" Akala a i breastfeeding.

Ma hāpai keiki, e e lawe i ka lāʻau wale ina ka Loaʻaʻia pomaikai a hiki i ka makuahine, ma mua o ka wā e hiki mai kamepiula a hiki i ka fetus.

Contraindications i ka hoʻohana 'ana o ka papa' mirapex "

Uluwehi O "mirapex" hiki ole ke lawe i ka hihia o ka hypersensitivity e pramipexole, e like me kanaka, ka poe i ole i 18 makahiki o ka makahiki.

Me ka kūikawā mālama nui ua waiho e hoʻohana i nā papa ma lalo o hoemi ke koko, a me nā konāhua 'ole.

ʻaoʻao 'ole "mirapex" lāʻau ma luna o ka'emi ko kahua

E hoomakaukau ai "mirapex" - papa a hiki i ka'emi'ōnaehana kēia reactions:

• hilahila;
• excessiveʻono no ka hiamoe a me ka nele ia mau mea;
• hallucinations;
• amnesia;
• asthenia;
• pōniuniu;
• extrapyramidal maʻi pale;
• hypoesthesia;
• tremor;
• myoclonus;
• dystonia;
• kaumaha;
• delirium;
• suicidal tendencies;
• hypokinesia;
• ataxia;
• ka iini;
• neuroleptic malignant maʻi pale.

Hope i ike i ke ano o ka hyperthermia, ka haunaele o ka ike paka i a me ka manaʻo, Muscle rigidity, autonomic lability, akathisia.

ʻaoʻao 'ole o nā huaale "mirapex" ma ka' ē aʻe nenoai o ke kanaka kino

Musculoskeletal'ōnaehana ke pane i ka hoʻohana 'ana i lapaau "mirapex" o ia hoike ana:

• hypertonic nāʻiʻo, kā lākou mau convulsions, twitching;
• hanana o ke arthritis, myasthenia gravis paha bursitis;
• ʻeha i loko o ka pahu, ai 'ole spine (i loko o ka lumbosacral).

Ka mea, hiki no hoi ana likeʻole i loko o ka digestive nenoaiu. A pau keia ia lŘlŘ:

• kahe o ka ikaika loa ka makemake;
• constipation;
• nausea;
• dyspepsia;
• flatulence;
• diarrhea;
• ka luaʻi;
• maloo waha;
• kua aloha i loko o ka'ōpū.

Naehana? Eaia "mirapex" o ka lāʻau 'ke ka hopena i loko o ka ulu ana o ka sinusitis, pharyngitis, rhinitis, maʻi palū-e like maʻi pale. Ua mea no hoi e hiki hanana o ka pokole o ka hanu, mahuahua cough a me ka leo loli.

He aha ka ke kanawai ma ka mea'ōnaehana mānowai koko'ōnaehana "mirapex" papa? Na Ke Kumu no ka hoʻohana ana i ka lāʻau 'hoʻomaopopo' o ia e pili ana i hiki 'ana tachycardia, arrhythmia, angina pectoris, orthostatic hypotension.

Otherʻaoʻao waiwai

I ka loaa ana i ka lāʻau "mirapex" ua complications kānāwai i loko o ka urogenital'ōnaehana, e like me ka hou pinepine na naau oʻu ka neʻe 'ana, maʻiʻaʻai. Pela i manao poho o ka libido a me ka potency.

Eia hou, oe e 'ike papalua hihiʻo, cataract, conjunctivitis, lōlō o ka noho, allergies, a me kaʻole lohe, i ka intraocular puʻe.

Other adverse reactions o ke kino.

• retroperitoneal fibrosis;
• pleural effusion;
• pulmonary infiltration;
• ke kaupaona poho;
• ʻike ākea edema.

Laʻau heluna, a noho kia'āina ' "mirapex" papa

E hoʻohana i ka lāʻau 'oe e pono ai loko, i kela la 3 manawa. Ka loiloi mua mahele lāʻau "mirapex PD" papa - 0,375 mg no ka lā. Ua hoʻonui i ka nui o ka lāʻau e pono ai (kela 7 lā) e loaa i ka makemake pākōlea hopena. Ma ka hebedoma elua o ka lapaʻau kēlā lā e e hoʻopauʻia 0,75 mg i loko o ke kolu - ia 1,5 mg no ka ha - ma 2.25 mg i loko o ka lima o ka pono, e inu lapaau "mirapex" 3 mg kela la i keia, ma ka hora aono a hiki - 3,75 mg, hiku o ka - 4.5 mg.

I ka maʻiʻaʻa puʻuwai ka hoʻokō 'ole, ka laʻau heluna ua like ka nānā' ana ma luna o ka hana nui o ka creatinineʻae. Ke mau dala o ka lāʻau e e kohoia ke kauka.

Hopena o ka overdose Akala a "mirapex"

Inā 'oe ke hoʻohana "mirapex" lāʻau laʻau heluna i wāwahiʻia, i kēia mau symptoms kānāwai presumably hallucinations, hyperkinesia, nausea, ka luaʻi, ua hoʻemi ke koko, a me ka arousal.

No keia kulana, ka antidote ua i hoʻouka kekahi. Hihia o ka lāʻau overdose "mirapex" ua i paa. Paipai symptomatic Inc, gastric lavage a me ka hōʻeuʻeu pono ana. Inā he mau hoailona o ka overdose o excitation o ka Central ko mākou hopohopo nenoaiu, ia mea pono e pili i ka hoomakaukau, neuroleptics.

Hana kūleʻa papa "mirapex" me nā ai '

Pramipexole pili wai koko kumuʻiʻo iki a me biotransformation. Nolaila, kona AaOIeIOUIeXAOAaIN me ka 'ē ai' e aloha ia mau keʻano o ka hanaʻana i olelo lealea.

Ai 'i inhibit a uhi i ka? Iecaianoaaiiie o ka hana waiwai ole cationic samovyvodyaschiesya ma kaʻaʻa puʻuwai tubules, hiki ke pane koke me huaale "mirapex". Na Ke Kumu no ka hoʻohana wehewehe ia ma keia hihia i ka mämä holo ka ho'ēmiʻana maopopo no huikalaia i nā'aʻaʻa a me liluwelo fluids ole mai nā medicaments a me kekahi o ia mau mea.

Inā ka poʻe me na huaale 'mirapex "hoʻohana i kēia mau ai', oe e hoʻolohe i ka hiki hallucinations, dyskinesia, manaʻo pīhoihoi. Inā mau hoailona ana, e hoemiia ka laʻau heluna o ka lāʻau e.

Hoʻokaulike papa "mirapex" me ka ai ' "Amantadine" a me ka "L-dopa"

He aha ka hana i ka wa a ka hui? Eaia "Levodopa" ai 'a me "selegiline" huaale "mirapex PD"? Instruction hākālia nō i nā pharmacokinetics o ka hana hope, aole ia e pili i ka mea mua,ʻaʻole hoʻi me ka lua. I ka Ia manawa ma luna o ka piha kaʻaluna a me excretion o ka lāʻau i loko o ka maoli ala "Levodopa" papa "mirapex" mea i 'ike'.

Pramipexole ia i? Anoee ka AaOIeIOUIeXAOAaIN o ka lāʻau "Amantadine". Akā, hoʻokaulike mea hiki ma ka Inc, no ka mea, i like maomeka o excretion.

I ka mahele lāʻau "mirapex" e hoomakaukau ai, a mahuahua nui, i ke noi dala "Levodopa" paipai, e emi. pono e mālama 'ia mau i ka helu o nā antiparkinsonian ai' ma ka ia pae.

Features hoʻokaulike makaukau "mirapex" me nā ai '

Aie i ka manawa kūpono o ka lōʻihi loa me ka lōʻihi mālama nui ua? Aeiiaiaoaony e hoʻohana papa "mirapex" ma ka hui pu ana, me ka kiaha dala, ka waiʻona, a me ka ai 'e kōkua i ka mahuahua pramipexole lehulehu i loko o ke koko (e laʻa me, ka lāʻau "Cimetidine").

I Kekahi Mau alakaʻi ma ka hoʻohanaʻana i "mirapex" papa

Mākou e hōʻike no ua i waiho i ka lāʻau, e lawe i ka huipūʻana me antipsychotics.

Ma ka iapaau ana o ka dopamine agonist ikeʻaoʻao 'ole i ka huikau a me hallucinations. Ma na hihia o "mirapex" papa i hoʻohui pū 'ia me ka lāʻau "Levodopa" na abnormalities ua oi hele pinepine mai ma ka kuʻina ma hope o ka maʻi ma mua i loko o ka kakahiaka monotherapy.

Ke Kauka Pono e hoʻomaopopo i ke ahonui o ka hiki hanana o ka pilikia makapō hallucinations. Kēiaʻaoʻao hookoia e loli ai ka hiki, e kipaku kaa, a e kuleana hoʻoholo.

Maʻoi discontinuation ana o na papa i loko o ka hihia o Parkinson ka maʻi i 'akomi i ka helehelena o ka symptoms e kohu neuroleptic malignant maʻi pale.

Anomalous hana ma o ka hoʻohanaʻana i "mirapex" lāʻau

Hoʻomanawanui iki mai a me ka poe mālama no ia, ka mea, mea pono e ike i ka hiki aku o dopaminergic ai ', a me "mirapex" papa (hōʻike manaʻo hōʻoia i kēia), pinepine kumu'āno'ē hana o ka hoʻomanawanui. Oe i 'ike hyperphagia (overeating' ino), pathological ikona (obsessive ake e hana i ka hailona o ke kūʻai lilo mai kekahi), compulsive nā polokalamu a me ka hypersexuality. Ma na hihia ia mea e pono e emi i ka laʻau heluna o ka lāʻau a me ke kiʻekiʻe o lawe ia ana.

Mālama nui i loko o ka hoʻohanaʻana i "mirapex" papa

Medicine "mirapex" E pau auaneʻi lākou me ka mālama nui, e hoʻomanawanui iki mai i ke alo o ka loa mai o ka mea'ōnaehana mānowai koko nenoaiu. Ma ka hoʻokō 'Inc me ka dopaminergic ai' he mea he pilikia o orthostatic hypotension. Nolaila, he koko, mana, ka oi aku ma ka loiloi mua kahua o ka lapaau.

Ka wā pilikia makapō hoʻopilikia mea pono, e mau ka huli ia hope koke iho o ka manawa i oleloia ai o ka papa "mirapex" a no hoi ia i ho'ākāka 'ʻanuʻu.

Nā mea maʻi e e haawiia i ka mea i ka lāʻau i i kekahi kiaha dala ia. A ua noho hihia o ka ulia hiamoe, a excessive sleepiness ma ka lā a hiki i ka lā hana. Me keia kānāwai i kekahi manawa i loko o ka hooponopono ana o ka luna 'hana a kipaku kaa.

I ka manawa kūpono o ka ulu melanoma

E like me ka hopena o epidemiological haʻawina i hōʻike i nā mea maʻi me Parkinson ka maʻi i ma kamepiula o ke melanoma. Ua mea i ke kumu o keia maʻi, a 'ē aʻe, e like me ka hoʻohana' ana o "mirapex" ka lāʻau i ole, ua hoʻokumu.

E hooikaika ana i ka maʻi pale o "restless wāwae"

Pehea i ka maʻi pale o "restless wāwae" lāʻau "mirapex"? E hoike hōʻike i dopaminergic ai 'i ka hōʻoi' ia. Keia ua hoikeia mai ma ka palapala o ka hoouka kaua mua ana o symptoms ma ke ahiahi maʻi pale a me kekahi manawa i loko o ka auwina la. Ma kēia hihia, na symptoms hohola iho la i na lala. Ka paa no 26 pule i lapaʻau noho mana ana ao, a i ke hoʻololi i ka hoʻopaʻa haʻawina i kēia keia, he nuiʻana ma waena pramipexole a me ka placebo hui ma 'ō o ka hiʻona o ka maʻi pale i, ua hōʻike'.

Waho pūnaewele kumu a me ka holopapa ola

"Mirapex" papa pili i ka makaukau ana o ka papa B. Store ka mea, e ia i loko o ka pouli wahi. Ma keia hihia i ka mehana ea e ole oi aku mamua o 30 ° C.

Holopapa-ola o ka lāʻau '- 36 mahina (3 makahiki) mai ka la aku o ka? Iecaianoaaiiuo.

Ka hoʻohana o "mirapex" papa ma ka wā kamaliʻi a me nā kumu o ke kuai ana

Ka lāʻau 'Ua contraindicated no ka hoʻohana i loko o nā keiki. Ae ua haawiia i ka poe e loaa ana na papa, a ua i 18 makahiki o ka makahiki. Medicine "mirapex" hoʻokuʻuʻia i loko o keʻena kūʻai lāʻau lapaʻau ma ka hōʻike o ke kuhikuhi.

Uluwehi O analogues "mirapex"

Oe hiki ole, no ka mea ke kumu, e loaʻa i ka papa o "mirapex"? He aha e puku i ka lāʻau, oe, mai hai aku i ka pharmacist a me kauka. A mākou e kaumaha aku na kēia mau analogues.

1. "Motopram" huaale. Nāʻikepili no ka hoʻohana: Parkinson ka maʻi. Ua hiki ke hana wale a hui me ka lapaʻauʻia lapaau 'levodopa'. Ua ua i hoʻohana 'ia no ka loa a me ka lōpū idiopathic ano o ka maʻi pale o "restless wāwae".
2. "Oprimeya" huaale. Manao: antiparkinsonian laau stimulant dopaminergic EYI i loko o ka Central ko mākou hopohopo nenoaiu.
3. "Pramipexole" huaale. Ka pākōlea Agena hoʻohana ma Parkinson ka maʻi. Ua Ua manaoio aku i keʻano papa hana o ka 'ana ua pololei ua hoʻopili i ka hiki ana o ka waiwai pramipexole hoʻoulu dopamine receptors i loko o ka striatum.

Papa "mirapex" - analogues a mua? No ka hoʻoponopono '!

I ka luna helu 'ia ma nā huahana, i nā analogues o' mirapex "papa. Ka mea, i ka ia kū hoʻokahi, kūwaho hoʻi 'ole-kūpono inoa (a ATC-code), a ua paipaiʻia ma ka MEA (World Health Organization).

Inā 'oe pono e undergo lapaʻau ka hoʻohana' ana o na papa io "mirapex" analogs hiki no hoi ia i ka makemake nui. Akā, ma mua o nā mea i'ōleloʻia ai o Inc oe e puku i, eʻoiaʻiʻo, e kukakuka me ka hoʻomalu. Ma lalo i ka noho ana hana ole naʻu! Kēia hiki i irreversible io hopena no kou ola.

Aʻo! He 'atikala He ua inā he ho'ākāka' ana o "mirapex" e hoomakaukau ai, a Nohie hoʻokolohua o ka kūhelu olelo ao no ka hoʻohana. Lāʻau 'ikepili ua hooku iho la ia ia no ka hana o ka nāʻana. I ole hihia e i hana ia e like me ke alakai ana i ka hoʻoponopono-ka lapaʻauʻia.