Papa "Zilt": kauoha no ka hoʻohana

Mea'ōnaehana mānowai koko maʻi (CVD) o kekahi no o ka haunaele ma cardiac haʻawina a me ke koko moku. No ka mea'ōnaehana mānowai koko maʻi nā coronary naau maʻi (naʻau ho'āhewa wale), kiʻekiʻe ke koko, (hypertension), cerebrovascular maʻi (hahau), rheumatic naau maʻi, ʻike ākea arterial maʻi, naau nele, a me ka naau maʻi (congenital). CVD e ulu like me ka hopena o ka paka i, physical inactivity, unhealthy aiʻano.

CVD e kamailio ana ma naʻano likeʻole. No ka laʻana, maʻi naau hoʻokō 'ole' e anaʻia ma ka lapaʻauʻia. ʻO ka pahuhopu nui o kēia iapaau ana mea e emi i ka haawe ana ma luna o ka naʻau a me ka hoʻoikaika 'ana i kona kuleana pili i pumping. Maʻi e like me ischemic hahauʻana a me ka myocardial infarction kekahi mea hiki ke hana hoʻomākaukau. Uluwehi O "Zilt" Ua hōʻike hewa papahana no keia mea.

"Zilt": kauoha no ka hoʻohana

"Zilt" Ua loaʻa like Auana-lole komoʻuʻuku nona na papa, i ka'ōpala hiki ke kapa hoʻohanohano ma ka helu o nā papa - ka palena iki o ka 14, i kā mākou o ka 90. kēlā papa he 75 nā huna o ka clopidogrel.

Ma ka nāʻana, "Zilt" papa i ka lokomaikaiia, i ka hoihoi hou ia ana o ka platelet hana ma hope o kekahi mau lā (7 i 10) ma hope o ka hoʻomanawanui papani iho la i ka hoʻohana 'ana i ka lāʻau. Ka lāʻau 'hoʻohana e hana mea'ōnaehana mānowai koko maʻi, ua antiagregatsionnym physiological hopena. I ka papa kuhikuhiEʻeleu 'Oponopono o ka la hoomalolo "Zilt" mea hoʻohana palapala noi i hea clopidogrel kāohi' ia paha ka paa o ka ADP e platelet receptors, i nā hualoaʻa ma ka inhibition o ADP-e kaukaʻi platelet aggregation.

Ka laʻau heluna no nā mākua - hoʻokahi papa (75 mg) no ka lā hoʻokahi, me ka mōhai mea,ʻaʻole e kaukaʻi. Duration o ka lapaʻau 'ana mau 12 mahina akā, i ke like ka nānā' ana ma luna o ke 'ano o ka maʻi a me kona oolea. ʻO kā mākou hopena hiki ke manao ia ma hope o 3 mahina.

E zilt aʻo no ka hoʻohana 'e waiho no ka Kāohiʻana o ka mea'ōnaehana mānowai koko maʻi: ischemic hahauʻana, mea'ōnaehana mānowai koko make i loko o nā mea maʻi me ka loa hoikeana o ka atherosclerosis, myocardial infarction. No hoi, "Zilt" ua hōʻike ma nā mea maʻi me kaʻike ākea arterial maʻi.

Kēia lāʻau ua contraindicated ma ke alo o ka hypersensitivity e clopidogrel 'ole' ē aʻe eiiiiiaiou o ka la hoomalolo. Eia kekahi, i ke kumu no ka contra hiki e pathological kahe ana ke koko, ake dysfunction (kaumaha), hāpai keiki, a lactation, e like me ka makahiki o ka makahiki 18.

Mālama nui E e hoʻohana zilt me ka hoomakaukau ana i loaʻa ka warfarin, heparin 'ole' ē aʻe thrombolytic hope, ai ole i ka pilikia o ke kahe ana ke koko. No clinically nui 'ole i loko o ka hihia o ka lāʻau me ka nifedipine, atenolol, digoxin, cimetidine, phenobarbital, theophylline paha estrogens. Pakele i ka hana me ka tolbutamidom a me ka fenotionom. Eia hou, i ka mahu omo o ka clopidogrel aloha ia antacids.

Hoike wale hihia o ka overdose "Zilt" e hoomakaukau ai: Ua lawe 14 papa (1050 mg o clopidogrel). Complications a me symptoms o intoxication ma keia hihia i ole malama, a uaʻaʻohe hemahema no kūikawā lapaau. No ka mea lāʻau mea i maopopo antidote. Inā pono, e hoʻopau i ke kanawai o ke clopidogrel, platelet transfusion nuipa a hua.

Zilt manual ia kekahi e hoahu i loko o ka me, maloo wahi, palekana mai Map. Allowable pūnaewele ka mahana o 25 ° C. Ka la hoomalolo He pono no ka makahiki ekolu. E hoʻomaopopo mai zilt aʻo no ka hoʻohana waiho wale ma luna o ka hoike ana o ke kauka - e ole ka hoʻoponopono-lapaʻau.