Prednisolone: aʻo no ka hoʻohana 'ana, ka mea pharmacological waiwai

Release palapala "Prednisolone" lāʻau: pahee lāʻau lapaʻau 'ano apau loa - poni.

Farmsvoystva

Prednisolone mea he dehydrogenated mea like o ka hydrocortisone. Antiallergic, antiinflammatory, antiexudative a me ka antipruritic ai ka wā hoʻohana topically mea poni "prednisolone" aʻo ke kumu o ka emi i loko o ke kahua, kalaʻana aku a me ka mama no hoi o ka li nui uao (kinin, he histamine, lysosomal nā'ūhū, prostaglandins). I inhibited aeea Polenekia i ka hoʻoʻino epicenter emi vasodilation, a māhuahua vascular permeability e ia lŘlŘ ma ka li nui. Hoemi i ka exudation mea ku pono i ka vasoconstrictor hana o "Prednisolone" lāʻau. Manual Hōʻike i ka lāʻau mea he immunosuppressive kanawai ma inhibiting i ka hana o ka antigen-lāʻau lapaʻau kino eiiieaena a me ka loaa ana ma ka paia o ka moku i ke koko, aʻo ke kumu o allergic vasculitis. Ke k inhibits ka hana o macrophages, cytokines, pale umauma hoʻokahi aeee i i ka hooulu ana o allergic naoh type lele dermatitis. Penei sensitized T-lymphocytes a me macrophages hiki ole kiʻi komo ana i ka pale kaua keena.

Pharmacokinetics

A hiki i ka noi o ka mea poni "Prednisolone" ke kemu, a me kaʻeleu waiwai i loko o ke koko. I ke koko wai koko prednisolone nui loa o nā ke albumin a me ka transcortin. Biotransformation prednisolone ia lŘlŘ ma'okesaside,ʻano nui i loko o ke akepaa, kahi glucuronidation a sulfation ia lŘlŘ oxidized 'ano apau loa. Ma ka palapala o metabolites excreted i loko o ka mimi a me feces, he hapa - i loko o ka unmodified moku'āina. Prednisolone ae ma ka placental ke'ākeʻakeʻa mai i loko o liʻiliʻi nā hoʻohui like, ka mea hiki ke loaʻa i loko o ka umauma ka waiu o na wahine.

Prednisolone: hoike

Ka lāʻau 'Ua hoʻohana i ka hihia o ka:

- allergic a irritant ka leo dermatitis,

- eczema,

- atopic dermatitis,

- seborrheic dermatitis,

- psoriasis.

Prednisolone: ke aʻo

I ka mea poni ua pili i kaʻeha paena kōā kaulike 1-3 manawa / lā. Duration o ka lapaʻau ua kena ae la ma ke ano o ka maʻi, a IeAUPIIe, IAa IO mau no 8-14 lā. E e hoemi poni ma ka iapaau ana o na keiki lōʻihi like 'ole o ka hana maikaʻiʻole i 3-7 lā, mai ke kino i ke keiki ka mea oi ikepili koʻikoʻi ia o ka lāʻau "Prednisolone". Instruction ia kekahi haalele lalana ana ia ia, ke haka pono maila a me occlusive dressings.

Hiʻona o ka palapala noi

ʻAʻole e ka lōʻihi like 'ole o ka hana maikaʻiʻole me ka mea poni e oi mamua o 14 mau lā ma ka mea e ole ai e hikiʻaoʻao' ole, mai ka hana o ka "Prednisolone" lāʻau. Aʻo prescribes e hana ma lalo o 'inikua hooponopono wale.

ʻaoʻao waiwai

I hookuu i ka lāʻau ua pono tolerated. Kākaʻikahi ka, o ka oi aku ma hope o hooloihi ae i ana, hiki i ka ohane, e aa ana ka waiʻona ma, erythema. Ma kekahi hoʻomanawanui iki mai i kaʻaoʻao waiwai i hoike i folliculitis, hypertrichosis, perioral dermatitis, allergic reactions i ka lapaʻauʻia eiiiiiaiou. Ka luna symptoms mai i koi lapaau a koke wehe 'ia ma ka hoopau ana o noi o ka lāʻau. Ua hoʻomanaʻoʻia ai ia i ke noi ana o ka poni a hiki i ka loli ana o ili a me ka lōʻihi-kau hana (oi loa i loko o ke pio ana o nā'āpana o ka ili) e ikeaʻaoʻao hopena o ka systemic ano.

Hana kūleʻa me nā ai '

Prednisolone i ka waiwai, e hoʻokō anticoagulant hopena o anticoagulants. Ua kūpono o ka manawa kūpono o ke kahe ana ke koko iā lawe salicylates. Ua maoli ka likelihood o electrolyte pūnao kāna hana me ka concomitant hooponopono o diuretics. Aia He He lālā pilikia o kaʻawahia i ka wa a me ka hoʻohana ' cardiac glycosides. Ua hoʻemi hypoglycemic antidiabetic ai a me ka emi ka antibacterial haʻawina o rifampicin. 'Aʻole i haawiia no ka hoʻohana i ka huipūʻana me antacids.

Contraindications

Lapaʻau "Prednisolone" mea poni i aʻo 'ia kēia i loko:

- hypersensitivity;

- mea koʻohune, mea hoʻomaʻi, fungal ili lesions;

- tuberculosis, syphilis, ili hikoko, hāpai keiki, e like me ka huehue a me ka a pink huehue.

overdose

Hihia o ka overdose i IKE OLE IA.

waho pūnaewele ana

Mālama ma ka papa inoa B, ma 5-15ºS. Holopapa ola - 2 makahiki. Ma ka hala o ka holopapa ola ,ʻaʻole i hoʻohana.

na kumu o ka lako hou i

Kuhikuhi.