Koko hōʻike. Koko clotting. Ho omńkalakala i ke koko o Kaoleioku: coagulation

Koko - ka mea, o ke kumu nui? Aneii lepo o ke kanaka kino. Noke ai hoʻolahaʻia i loko o ia, a haawi i ke keena me ka o oxygen, a pau i ka nui metabolites, e hanaʻia kona walaʻauʻana i hana '. Eia hou, i ke koko mea i ka palekana i ka ka hoike ana o ka ai iiiaanoaa o pathogens o infectious maʻi, e like me pale kahe ana ke koko ma ka hihia o ka poho o kekahi moku. Eia nae, o ka kūikawā coagulation'ōnaehana oia hoi o ka luna '' ia paha o nā polokina. Ano, ke kūkākūkā i kēia i loko o hou au mamuli.

Ka 'ole o ka hemostasis

Ka mea, e loaʻa mai i ka'ōnaehana o hemostasis. Ua he a mau eiiiiiaiou antagonistic i kekahi i kekahi - coagulation a me ka anticoagulation. Akā, i ka mea ia manawa, e hoʻokō kekahi i kekahi, no laila, i ole i ke koko i hoʻololi i kona qualitative kiko'î, a ua hiki keʻai ma luna o nā nā'aʻaʻa. Ka mea mua i loaʻa ka lanakila me kahe ana ke koko i ka wa pono, e hana i kekahi koko clot obturation hamama lumen i loko o ka ipu paia. Ka lua ua ho'ā 'ia paha ma hope koke o ka hana mua, ma ia pale clotting a me ka māhuahua' ana o ka thrombosis ua hanahana loa ka hopena, e like me hahauʻana a me ka myocardial infarction.

No laila, i ka maʻi nui ia nohona ma Ka Ikepili o ke koko. Koko clotting a me kona mea koʻohune seeding - o ka pahu hopu o keia mahele. oe ke hana i ka pololei a me kaʻike, kūpono hana ma muli o konaʻikepili.

Nā eiiiiiaiou i loko o ka nohona ma Ka Ikepili o ke koko

Mawaena o na eiiiiiaiou o ka coagulation'ōnaehana hoopiha nui i wahi like keena a me nā polokina. He kuhikuhi platelets, a, ma ka hou ana i kona iniiaiie hana, i hoomakaukau i ai endothelium naʻau i ka loko o nā ipu a pau i ke koko. Lākou helu Hiki ke loaʻa ma ka hele i ka lapaʻau koko helu. Clotting, naʻe, hilinaʻi nui ole wale ma luna o lākou helu, akā, no hoi i ko lakou mea e like ai. Penei, ka wā i inconsistency hoʻomaopop 'ana i hana i kēia mau keena hoʻomōhala thrombocytopathia, paʻakikī e hōʻike, a ua wehewehe aku ma ka lau, ia mea paakiki i ka pau ana i ke kahe ana ke koko, a hiki e ho'ōla alakai i ke poho o ke ola. Kekahi noʻonoʻo, a pau loa, a hiki i ka piha lapaʻau Ka Ikepili o ke koko - clotting manawa Lee-White. Ua Ua nānā 'ia e pono ?? na paipu me ka kūpapakū ia a ka mea Nonseparated anuanu clot.

ano aʻe

pū nā polokina e komo i loko o ka haku mele 'ana o ka coagulation'ōnaehana, haawiia i heʻumikumamākolu kumumea. Lākou kū hoʻokahi waiho i loko o ka mea e maʻamau ka mea, i loko o ka AEeOEXAaI moku'āina a loaʻa mea he kumu no kā lākou mau hana, e like me ka pono me loko o ka luna 'pae o ko lākou Launch, ma a ka mea hana e like catalysts no kēia mau reactions. Penei, keia nenoaiu, kŘpa a kaʻawale. Mea e like ai 'ano o ko lākou hanaʻana i komo i loko o ka puali ololi koko ho'āʻo - "ke koko clotting" a me "coagulation". Ua loaʻa o ke kaupalena helu o nā koho, akā, ke kauka nana nona ka ike e pili ana ia mau mea, hiki pololei ke kapa i ke kumu o kāna hana o ka hemostasis, a hiki i ka nń ku maʻi. Penei, ho omńkalakala i ke koko ho'āʻo ma "clotting" ninoaaeyao nui i wahi i loko o ka lapaʻau hana o kēlā me kēia hoʻomalu, a no laila, e kamaʻilio mākou ia i loko o oi au mamuli.

Key nā hoailona o ka coagulation

No laila, i loko o kēia study ninoieo o na kēia mau kī manaÿo.

• Mua. D-dimer mea nui he anakahi o ka thrombosis, a pela ua hoʻohana 'ia no ka kakahiakaʻike, o ka thrombosis. Hapai i loaʻa ma ka nui dala (3-4 manawa) ma ka hopena o ka wā o ka gestation, akā, i kēia mea he Lolina o ke kūmau. Ka loaʻaʻana o ka mea, he nui lehulehu o ka hoike mua ma luna o ka pathological papa o ka hāpai keiki. Eia hou, e hōʻike i ka hoomahuahua i ka maʻi e like me rheumatoid arthritis, hemorrhagic complications, loa nā mea palahēhē.
• I ka lua o ka manaʻo. Prothrombin manawa laua computation inideka INR a me ka ili n (prothrombin inideka) characterizes ka moku'āina o ke koko coagulation'ōnaehana a ua anaia mai ka manawa e Koagulometers a me nā papakuhikuhi. Hoakakaia like no ka loiloi 'ana o hemostasis, a ma o ka hana o kaʻauhau'ēʻaʻe anticoagulants.
• Ekolu. Fibrinogen - he luna 'kumuʻiʻo. He ka iwi kuamoo no ka ho okumu ana o ke koko clot - thrombus. Kona mea ulu ua pu ma ka hepatitis, hakuʻala maʻi, myocardial infarction, pāhawewe maʻi, Ka maʻi 'aʻai. Eia naʻe, e like me ka malama i hāpai keiki, menstruation, a no hoi me ka moʻolelo contraceptives me ka iniiaiie estrogen ke keʻena.

nā hoailona protivosvertyvaniya

• I ka ha o ka manaʻo. Lupus coagulant mea he pūʻulu o nā mea'aʻaʻa i kona mau platelets, i mea he kīnā o loa autoimmune kaʻina. Ka hapanui pinepine i loaʻa i loko o ka pathology o ka hāpai keiki, oa. E. Gestosis. Kona alo wehewehe lākou loa hemodynamic haunaele - edema, ke koko, kiʻekiʻe pahiki o miscarriage. No laila, i ke koko, "ke koko clotting" Ka Ikepili ua hana no nā mea a pau hapai wahine, e pale aku i kēia koho.
• Elima. Antithrombin-3, ma ka Akä, o ke kumuʻiʻo anticoagulation'ōnaehana a me ka thrombin inhibitor. Inā ka hoʻomanawanui e losing koko hōʻike, "ke koko coagulation," a me ka emi kūpono ma keia ke keʻena, ia Hōʻike he pilikia o ka thrombosis. Nō hoʻi, i ka wehewehena o ka antithrombin-3 mea nui no ka mana o nā mea maʻi e loaa ana lōʻihi-makahiki anticoagulant ai 'moʻo (ai' "TromboASS", "Cardiomagnyl", "clopidogrel").

summing mai

Ma waho aʻeo ia ka luna, aia no he ana aPTT i loa maopopo Hōʻike 'lawa / nele o nā kumumea o ke koko clotting. No ia mea, ia mea nui e hooholo i ka loa hemophilia likeʻole Kin, av Willebrand ka maʻi, i ke alo o ka oi coagulation nā mea kūpale a me anticoagulants? Eaia. It E e kaulana i hiki wale i ke koko clotting mea o loko e hōʻike. Eia naʻe, inā e manaʻo ai he 'aʻe ma ka hemostatic'ōnaehana, he mamao nele i ka ike i ke kauka.